Suppr超能文献

长期外周神经刺激治疗疼痛性神经损伤。

Long-term peripheral nerve stimulation for painful nerve injuries.

作者信息

Eisenberg Elon, Waisbrod Hannan, Gerbershagen Hans U

机构信息

Pain Relief Unit, Rambam Medical Center, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa Pain Research Group, Israel.

出版信息

Clin J Pain. 2004 May-Jun;20(3):143-6. doi: 10.1097/00002508-200405000-00003.

Abstract

BACKGROUND

Although peripheral nerve stimulation (PNS) has been used in the treatment of pain since 1965, only a few follow-up studies have been published. The aim of the present retrospective study was to carefully assess the long-term efficacy and safety of PNS in the treatment of painful nerve injuries.

METHODS

Patients suffering from intractable pain due to peripheral nerve injuries underwent PNS after careful selection. Long-term results were evaluated based upon patients' reports of pain intensity on a visual analog scale (VAS) and their consumption of analgesics. Two categories of results were chosen: good, referring to 50% or more relief of pain with abstinence from analgesic medications; and poor, with less than 50% improvement.

RESULTS

Of 154 referred patients, 46 (26 women and 20 men) were found suitable for PNS. Four etiologic factors were identified, the most common being nerve lesion following an operation in the region of the hip or knee. Other etiologies included entrapment neuropathy, pain following nerve graft, and painful neuropathy following a traumatic injection. The follow-up period was 3-16 years. Of the 46 patients who underwent surgery, the results were classified as good in 36 (78%) patients and as poor in 10 (22%) patients. Overall, pain intensity dropped from a VAS of 69 +/- 12 before surgery to 24 +/- 28 postoperatively (P < 0.001).

CONCLUSIONS

PNS can produce good pain relief in the majority of carefully selected patients suffering from isolated painful neuropathies.

摘要

背景

尽管自1965年以来外周神经刺激(PNS)已被用于疼痛治疗,但仅有少数随访研究发表。本回顾性研究的目的是仔细评估PNS治疗疼痛性神经损伤的长期疗效和安全性。

方法

因外周神经损伤而患有顽固性疼痛的患者在经过仔细筛选后接受PNS治疗。根据患者在视觉模拟量表(VAS)上报告的疼痛强度及其镇痛药消耗量来评估长期结果。选择了两类结果:良好,指疼痛缓解50%或更多且停用镇痛药;不佳,指改善不足50%。

结果

在154例转诊患者中,发现46例(26例女性和20例男性)适合接受PNS治疗。确定了四个病因因素,最常见的是髋部或膝部区域手术后的神经损伤。其他病因包括卡压性神经病变、神经移植后的疼痛以及创伤性注射后的疼痛性神经病变。随访期为3至16年。在接受手术的46例患者中,结果在36例(78%)患者中被分类为良好,在10例(22%)患者中被分类为不佳。总体而言,疼痛强度从术前VAS评分69±12降至术后24±28(P<0.001)。

结论

对于大多数精心挑选的孤立性疼痛性神经病变患者,PNS能有效缓解疼痛。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验