Slipman Curtis W, Rogers Denis P, Isaac Zacharia, Lipetz Jason S, Herzog Richard, Lenrow David A, Vresilovic Edward J
The Penn Spine Center, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Pain Med. 2002 Mar;3(1):23-9. doi: 10.1046/j.1526-4637.2002.02001.x.
Describe our experience using discography with intradiscal gadolinium and MR lumbar discography in patients with a history of severe anaphylactoid reaction to iodinated radiocontrast agents.
Observational study of 14 patients.
From 1997 to 1999, 14 patients were referred for lumbar discography with intradiscal gadolinium followed by MRI. Patients with a history of a severe anaphylactoid reaction to iodinated radiocontrast media or those who refused the use of iodinated contrast material were included in the study.
In fourteen patients, 58 discs were studied. The post discography MRIs identified seven annular tears and seven annular fissures. None of the fourteen patients reported symptoms suggestive of allergic reaction either during or after discography.
Discography using intradiscal administration of gadolinium followed by MRI provides a method of obtaining a clinically pertinent study in a subset of patients who likely would not be offered the procedure, secondary to severe anaphylactoid reactions to iodinated contrast materials.
描述我们在有对碘化造影剂严重类过敏反应病史的患者中使用椎间盘内注射钆剂行椎间盘造影及磁共振腰椎间盘造影的经验。
对14例患者的观察性研究。
1997年至1999年,14例患者被转诊接受椎间盘内注射钆剂后行腰椎间盘造影及磁共振成像检查。有对碘化造影剂严重类过敏反应病史或拒绝使用碘化造影剂的患者纳入本研究。
14例患者共研究了58个椎间盘。椎间盘造影后磁共振成像发现7例环状撕裂和7例环状裂隙。14例患者中无一例在椎间盘造影期间或之后报告有提示过敏反应的症状。
椎间盘内注射钆剂后行椎间盘造影及磁共振成像,为一部分因对碘化造影剂严重类过敏反应可能无法接受该检查的患者提供了一种获得临床相关研究结果的方法。