Loidl Peter
Department of Molecular Biology, Innsbruck Medical University, Peter-Mayr-Strasse 4b, A-6020 Innsbruck, Austria.
Trends Plant Sci. 2004 Feb;9(2):84-90. doi: 10.1016/j.tplants.2003.12.007.
The genome contains all the information needed to build an organism. However, during differentiation and development, additional epigenetic information determines the functional state of cells and tissues. This epigenetic information can be introduced by cytosine methylation and by marking nucleosomal histones. The code written on histones consists of post-translational modifications, including acetylation and methylation. In contrast to the universal nature of the DNA code, the histone language and its decoding machinery differ among animals, plants and fungi. Plant cells have retained totipotency to generate the entire plant and maintained the ability to dedifferentiate, which suggests that the establishment and maintenance of epigenetic information differs from animals. Here, I aim to summarize the histone code and plant-specific aspects of setting and translating the code.
基因组包含构建生物体所需的所有信息。然而,在分化和发育过程中,额外的表观遗传信息决定了细胞和组织的功能状态。这种表观遗传信息可通过胞嘧啶甲基化和对核小体组蛋白进行标记来引入。写在组蛋白上的密码由翻译后修饰组成,包括乙酰化和甲基化。与DNA密码的普遍性不同,组蛋白语言及其解码机制在动物、植物和真菌之间存在差异。植物细胞保留了产生整个植株的全能性,并保持了去分化的能力,这表明表观遗传信息的建立和维持与动物不同。在这里,我的目的是总结组蛋白密码以及该密码设定和解读过程中植物特有的方面。