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85例肺部病变的胸腔镜切除术

Thoracoscopic resection of 85 pulmonary lesions.

作者信息

Landreneau R J, Hazelrigg S R, Ferson P F, Johnson J A, Nawarawong W, Boley T M, Curtis J J, Bowers C M, Herlan D B, Dowling R D

机构信息

Section of Thoracic Surgery, University of Pittsburgh, Pennsylvania 15213.

出版信息

Ann Thorac Surg. 1992 Sep;54(3):415-9; discussion 419-20. doi: 10.1016/0003-4975(92)90430-c.

Abstract

Advances in endoscopic surgical equipment and laser technology have expanded the role of thoracoscopy to include thoracoscopic pulmonary resection. Eighty-five thoracoscopic pulmonary resections were performed on 61 consecutive patients with small lesions (less than 3 cm) in the outer third of the lung. Patients with preoperative histologic evidence of bronchogenic carcinoma were excluded unless there was impairment of cardiopulmonary function, advanced age, or concomitant extrathoracic malignancy. These thoracoscopic pulmonary resections were accomplished with the neodymium:yttrium-aluminum garnet laser (31), endoscopic stapler (29), or both (25). The mean diameter of the lesions was 1.3 cm (range, 0.4 to 2.7 cm). There has been one late death (38th postoperative day) unrelated to the operation. Morbidity consisted of postoperative atelectasis (2), pneumonia (2), bleeding requiring transfusion (1), and bronchopleural fistula of greater than 7 days duration (3). There were no wound problems. The mean period of chest tube drainage was 3.3 +/- 3.0 days. Mean postoperative stay was 5.7 +/- 4.9 days. The pathologic diagnosis was benign disease in 28 patients (interstitial fibrosis/pneumonitis, 15; radiation fibrosis, 1; sclerosing hemangioma, 1; rheumatoid nodules, 1; granuloma, 2; nocardia, 1; infarct, 1; hamartoma, 4; scar, 1; cytomegalovirus pneumonia, 1), metastatic malignancy in 20 patients, and bronchogenic carcinoma in 13 patients. Five patients found at thoracoscopic pulmonary resection to have bronchogenic cancer had adequate pulmonary function and therefore underwent formal segmentectomy (3) or lobectomy (2). Thoracoscopic pulmonary resection was the only operation performed on patients with benign disease, patients with metastatic lesions, and selected patients with limited stage bronchogenic carcinoma at increased risk for thoracotomy.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

内镜手术设备和激光技术的进步扩大了胸腔镜的作用,使其包括胸腔镜肺切除术。对61例连续的肺部外周小病变(小于3厘米)患者进行了85例胸腔镜肺切除术。除非存在心肺功能损害、高龄或合并胸外恶性肿瘤,术前有支气管源性癌组织学证据的患者被排除在外。这些胸腔镜肺切除术采用钕钇铝石榴石激光(31例)、内镜吻合器(29例)或两者联合使用(25例)完成。病变的平均直径为1.3厘米(范围为0.4至2.7厘米)。有1例晚期死亡(术后第38天)与手术无关。并发症包括术后肺不张(2例)、肺炎(2例)、需要输血的出血(1例)以及持续超过7天的支气管胸膜瘘(3例)。没有伤口问题。胸管引流的平均时间为3.3±3.0天。术后平均住院时间为5.7±4.9天。病理诊断为良性疾病的有28例患者(间质性纤维化/肺炎,15例;放射性纤维化,1例;硬化性血管瘤,1例;类风湿结节,1例;肉芽肿,2例;诺卡菌病,1例;梗死,1例;错构瘤,4例;瘢痕,1例;巨细胞病毒性肺炎,1例),转移性恶性肿瘤20例,支气管源性癌13例。5例在胸腔镜肺切除术中发现患有支气管源性癌的患者肺功能良好,因此接受了正规的肺段切除术(3例)或肺叶切除术(2例)。胸腔镜肺切除术是对良性疾病患者、转移性病变患者以及部分开胸手术风险增加的局限性支气管源性癌患者进行的唯一手术。(摘要截选至250字)

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