McAlister F A, Murphy N F, Simpson C R, Stewart S, MacIntyre K, Kirkpatrick M, Chalmers J, Redpath A, Capewell S, McMurray J J V
Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2R7.
BMJ. 2004 May 8;328(7448):1110. doi: 10.1136/bmj.38043.414074.EE. Epub 2004 Apr 23.
To examine whether there are socioeconomic gradients in the incidence, prevalence, treatment, and follow up of patients with heart failure in primary care.
Population based study.
53 general practices (307,741 patients) participating in the Scottish continuous morbidity recording project between 1 April 1999 and 31 March 2000.
2186 adults with heart failure.
Comorbid diagnoses, frequency of visits to general practitioner, and prescribed drugs.
2186 patients with heart failure were seen (prevalence 7.1 per 1000 population, incidence 2.0 per 1000 population). The age and sex standardised incidence of heart failure increased with greater socioeconomic deprivation, from 1.8 per 1000 population in the most affluent stratum to 2.6 per 1000 population in the most deprived stratum (odds ratio 1.44, P = 0.0003). On average, patients were seen 2.4 times yearly, but follow up rates were less frequent with increasing socioeconomic deprivation (from 2.6 yearly in the most affluent subgroup to 2.0 yearly in the most deprived subgroup, P = 0.00009). Overall, 812 (80.6%) patients were prescribed diuretics, 396 (39.3%) angiotensin converting enzyme inhibitors, 216 (21.4%) beta blockers, 208 (20.7%) digoxin, and 86 (8.5%) spironolactone. The wide discrepancies in prescribing between different general practices disappeared after adjustment for patient age and sex. Prescribing patterns did not vary by deprivation categories on univariate or multivariate analyses.
Compared with affluent patients, socioeconomically deprived patients were 44% more likely to develop heart failure but 23% less likely to see their general practitioner on an ongoing basis. Prescribed treatment did not differ across socioeconomic gradients.
研究在初级医疗保健中,心力衰竭患者的发病率、患病率、治疗及随访情况是否存在社会经济梯度差异。
基于人群的研究。
1999年4月1日至2000年3月31日期间参与苏格兰持续发病率记录项目的53家普通诊所(307,741名患者)。
2186名成年心力衰竭患者。
合并诊断、就诊于全科医生的频率及所开药物。
共观察到2186例心力衰竭患者(患病率为每1000人中有7.1例,发病率为每1000人中有2.0例)。心力衰竭的年龄和性别标准化发病率随社会经济剥夺程度的增加而升高,从最富裕阶层的每1000人中有1.8例增至最贫困阶层的每1000人中有2.6例(比值比1.44,P = 0.0003)。患者平均每年就诊2.4次,但随着社会经济剥夺程度的增加,随访率降低(从最富裕亚组的每年2.6次降至最贫困亚组的每年2.0次,P = 0.00009)。总体而言,812例(80.6%)患者使用了利尿剂,396例(39.3%)使用了血管紧张素转换酶抑制剂,216例(21.4%)使用了β受体阻滞剂,208例(20.7%)使用了地高辛,86例(8.5%)使用了螺内酯。在对患者年龄和性别进行调整后,不同普通诊所之间在开药方面的巨大差异消失。在单因素或多因素分析中,开药模式在不同剥夺类别之间并无差异。
与富裕患者相比,社会经济贫困患者发生心力衰竭的可能性高44%,但持续就诊于全科医生的可能性低23%。不同社会经济梯度之间的规定治疗并无差异。