Murphy N F, Simpson C R, McAlister F A, Stewart S, MacIntyre K, Kirkpatrick M, Chalmers J, Redpath A, Capewell S, McMurray J J V
Department of Cardiology, Western Infirmary, Glasgow, UK.
Heart. 2004 Oct;90(10):1129-36. doi: 10.1136/hrt.2003.029553.
To examine the epidemiology, primary care burden, and treatment of heart failure in Scotland, UK.
Cross sectional data from primary care practices participating in the Scottish continuous morbidity recording scheme between 1 April 1999 and 31 March 2000.
53 primary care practices (307,741 patients).
2186 adult patients with heart failure.
The prevalence of heart failure in Scotland was 7.1 in 1000, increasing with age to 90.1 in 1000 among patients > or = 85 years. The incidence of heart failure was 2.0 in 1000, increasing with age to 22.4 in 1000 among patients > or = 85 years. For older patients, consultation rates for heart failure equalled or exceeded those for angina and hypertension. Respiratory tract infection was the most common co-morbidity leading to consultation. Among men, 23% were prescribed a beta blocker, 11% spironolactone, and 46% an angiotensin converting enzyme inhibitor. The corresponding figures for women were 20% (p = 0.29 versus men), 7% (p = 0.02), and 34% (p < 0.001). Among patients < 75 years 26% were prescribed a beta blocker, 11% spironolactone, and 50% an angiotensin converting enzyme inhibitor. The corresponding figures for patients > or = 75 years were 19% (p = 0.04 versus patients < 75), 7% (p = 0.04), and 33% (p < 0.001).
Heart failure is a common condition, especially with advancing age. In the elderly, the community burden of heart failure is at least as great as that of angina or hypertension. The high rate of concomitant respiratory tract infection emphasises the need for strategies to immunise patients with heart failure against influenza and pneumococcal infection. Drugs proven to improve survival in heart failure are used less frequently for elderly patients and women.
研究英国苏格兰地区心力衰竭的流行病学、初级保健负担及治疗情况。
采用1999年4月1日至2000年3月31日参与苏格兰持续发病率记录计划的初级保健机构的横断面数据。
53家初级保健机构(307,741名患者)。
2186例成年心力衰竭患者。
苏格兰地区心力衰竭患病率为千分之7.1,随年龄增长而升高,在85岁及以上患者中升至千分之90.1。心力衰竭发病率为千分之2.0,随年龄增长而升高,在85岁及以上患者中升至千分之22.4。对于老年患者,心力衰竭的就诊率等于或超过心绞痛和高血压。呼吸道感染是导致就诊的最常见合并症。男性中,23%的患者服用β受体阻滞剂,11%服用螺内酯,46%服用血管紧张素转换酶抑制剂。女性相应比例分别为20%(与男性相比p = 0.29)、7%(p = 0.02)和34%(p < 0.001)。75岁以下患者中,26%服用β受体阻滞剂,11%服用螺内酯,50%服用血管紧张素转换酶抑制剂。75岁及以上患者相应比例分别为19%(与75岁以下患者相比p = 0.04)、7%(p = 0.04)和33%(p < 0.001)。
心力衰竭是一种常见疾病,尤其随着年龄增长。在老年人中,心力衰竭的社区负担至少与心绞痛或高血压一样大。呼吸道感染的高发生率强调了对心力衰竭患者进行流感和肺炎球菌感染免疫策略的必要性。已证实可改善心力衰竭患者生存率的药物在老年患者和女性中使用频率较低。