Bodén Henrik, Adolphson Per, Oberg Michael
Division of Orthopaedics, Karolinska Institutet at Danderyd Hospital, 18288, Danderyd, Stockholm, Sweden.
Arch Orthop Trauma Surg. 2004 Jul;124(6):382-92. doi: 10.1007/s00402-004-0666-5. Epub 2004 Apr 27.
Uncemented stems in total hip arthroplasty (THA) are used increasingly often because they are believed to offer a reliable long-term fixation. However, periprosthetic bone remodelling has been a worrying issue. A proximal demineralization has been noted in femurs with well-fixed stems, and it has been explained as by-passing of mechanical forces along the fixed implant (stress-shielding). Aseptic loosening has been a major problem in several uncemented series with earlier designs. The objective for this study was to investigate how the host bone adapts to a loose stem compared with a well-fixed stem after a long time.
An investigation with dual-energy X-ray absorptiometry (DEXA), scintimetry and radiological assessment was carried out in 20 patients 8 years after a THA for arthrosis with two different uncemented stems. Ten patients received a stem coated with polytetrafluoroethylene (Anaform); all prostheses showed migration and were considered unstable. Ten patients received a hydroxyapatite-coated stem (Bi-Metric); no prosthesis migrated.
Different remodelling patterns were seen. In the unstable group, the periprosthetic bone mineral density (BMD) was significantly reduced along the entire stem, while in the stable group only proximal bone loss was seen. The scintigraphic uptake was increased under the stem tip in both groups, and among unstable stems uptake was also increased in the calcar region.
The assessment of periprosthetic bone remodelling after uncemented THA with long-term observation shows a different host-bone response in stable versus unstable femoral implants. Prior to a femoral revision, measurement of the BMD could be beneficial; it may guide the surgeon when deciding which surgical technique to use.
在全髋关节置换术(THA)中,非骨水泥型股骨柄的使用越来越频繁,因为人们认为它能提供可靠的长期固定。然而,假体周围的骨重塑一直是个令人担忧的问题。在股骨柄固定良好的股骨中,已观察到近端脱矿现象,这被解释为机械力沿固定植入物绕过(应力遮挡)。在一些早期设计的非骨水泥型系列中,无菌性松动一直是个主要问题。本研究的目的是调查与长期固定良好的股骨柄相比,宿主骨在长期使用后如何适应松动的股骨柄。
对20例因骨关节炎接受THA手术且使用两种不同非骨水泥型股骨柄的患者进行了双能X线吸收法(DEXA)、闪烁扫描法和放射学评估,时间为术后8年。10例患者接受了涂有聚四氟乙烯的股骨柄(Anaform);所有假体均有移位,被认为不稳定。10例患者接受了羟基磷灰石涂层股骨柄(Bi-Metric);无假体移位。
观察到不同的重塑模式。在不稳定组中,假体周围骨密度(BMD)沿整个股骨柄显著降低,而在稳定组中仅观察到近端骨质流失。两组在股骨柄尖端下方的闪烁扫描摄取均增加,在不稳定股骨柄中,小转子区域的摄取也增加。
对非骨水泥型THA术后假体周围骨重塑进行长期观察显示,稳定型与不稳定型股骨植入物的宿主骨反应不同。在进行股骨翻修之前,测量BMD可能有益;它可能在外科医生决定使用哪种手术技术时提供指导。