Peppercorn Mark A
Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Rabb 420, Boston, MA 02215, USA.
J Clin Gastroenterol. 2004 May-Jun;38(5 Suppl 1):S8-10. doi: 10.1097/01.mcg.0000123993.13937.ec.
An overlap of inflammatory bowel disease and diverticular disease has long been recognized. Crohn's disease and diverticulitis share clinical and radiologic features but usually differ in histopathologic findings. There is a suggestion, however, that even the characteristic pathology of Crohn's disease can be a secondary reaction to diverticulitis. It is possible, moreover, that the presence of Crohn's disease in association with diverticulosis predisposes to the development of diverticulitis. Finally, an apparently distinct form of segmental colitis associated with sigmoid diverticula has been described further contributing to the overlap of inflammatory bowel disease and diverticular disease.
炎症性肠病和憩室病的重叠现象早已为人所知。克罗恩病和憩室炎具有共同的临床和放射学特征,但组织病理学表现通常有所不同。然而,有观点认为,即使是克罗恩病的典型病理改变也可能是憩室炎的继发反应。此外,克罗恩病与憩室病并存可能会增加憩室炎的发病风险。最后,一种与乙状结肠憩室相关的明显独特的节段性结肠炎已被描述,这进一步加剧了炎症性肠病和憩室病的重叠。