Meyers M A, Alonso D R, Morson B C, Bartram C
Gastroenterology. 1978 Jan;74(1):24-31.
The involement of diverticula by granulomatous colitis may cause an increased incidence of diverticulitis. Of 21 patients with Crohn's disease and associated diverticulosis who underwent resection, sigmoid diverticulitis was pathologically confirmed in 10 (48%). The clinical recognition of the coexistence of the two diseases is often difficult. The radiological signs of peridiverticulitis complicating granulomatous colitis usually show clear evidence of the underlying pathological changes. They include localized diverticular performation, perhaps with multiple communications via a paracolonic sinus tract, mass pressure from the paracolicabscess, and occasionally some degree of communication with deep fissuring ulcers of Crohn's disease. Because diverticula breach the colonic wall, histological analysis confirm that their involvement by the transmural process of granulomatous colitis predisposes to peridiverticulitis and/or abscess formation.
肉芽肿性结肠炎累及憩室可能导致憩室炎发病率增加。在21例患有克罗恩病并伴有憩室病且接受切除术的患者中，10例（48%）经病理证实存在乙状结肠憩室炎。临床上常常难以识别这两种疾病的并存情况。肉芽肿性结肠炎并发憩室周围炎的放射学征象通常能清晰显示潜在的病理变化。这些征象包括局限性憩室穿孔，可能通过结肠旁窦道形成多处连通，结肠旁脓肿产生的肿块压迫，以及偶尔与克罗恩病的深部裂隙溃疡存在一定程度的连通。由于憩室穿破结肠壁，组织学分析证实肉芽肿性结肠炎的透壁性病变累及憩室会引发憩室周围炎和/或脓肿形成。
