Pellock John M, Marmarou Anthony, DeLorenzo Robert
Department of Neurology, Virginia Commonwealth University, Medical College of Virginia, Richmond, VA, USA.
Epilepsy Behav. 2004 Apr;5(2):192-6. doi: 10.1016/j.yebeh.2003.12.012.
Prompt intervention in seizure emergencies is critical to reducing morbidity and mortality risks associated with status epilepticus. To determine the need for wider education about the benefits of at-home treatment, we examined the time from seizure onset to initial treatment in a cohort of patients with epileptic seizures. The seizure database of patients admitted in the greater Richmond, Virginia, area during a 5-year period (1989-1994) was queried to extract time to seizure treatment. Records were available for 889 patients. Patients were divided into two subgroups: children (age < 16 years, 29.7% of the cohort) and adults. Time to seizure treatment varied broadly; only 41.5% of all patients received their first antiepilepsy drug within 30 minutes. Time to treatment did not significantly differ between age groups. This baseline study supports the need for patient education regarding seizure emergencies and wider availability of at-home treatment options to shorten time to seizure treatment.
在癫痫发作紧急情况中进行及时干预对于降低与癫痫持续状态相关的发病和死亡风险至关重要。为了确定是否需要更广泛地开展关于家庭治疗益处的教育,我们研究了一组癫痫发作患者从发作开始到初始治疗的时间。查询了弗吉尼亚州里士满地区在5年期间(1989 - 1994年)收治患者的癫痫发作数据库,以提取癫痫发作至治疗的时间。有889例患者的记录可用。患者分为两个亚组:儿童(年龄<16岁,占队列的29.7%)和成人。癫痫发作至治疗的时间差异很大;所有患者中只有41.5%在30分钟内接受了第一种抗癫痫药物治疗。不同年龄组之间的治疗时间没有显著差异。这项基线研究支持有必要对患者进行癫痫发作紧急情况的教育,并更广泛地提供家庭治疗选择,以缩短癫痫发作至治疗的时间。