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含精油漱口水对定期刷牙和使用牙线的患者减少牙菌斑和牙龈炎的辅助益处:一项为期六个月的研究。

Adjunctive benefit of an essential oil-containing mouthrinse in reducing plaque and gingivitis in patients who brush and floss regularly: a six-month study.

作者信息

Sharma N, Charles C H, Lynch M C, Qaqish J, McGuire J A, Galustians J G, Kumar L D

机构信息

BioSci Research Canada, Mississauga, Ontario.

出版信息

J Am Dent Assoc. 2004 Apr;135(4):496-504. doi: 10.14219/jada.archive.2004.0217.

Abstract

BACKGROUND

Mechanical methods of oral hygiene can be complemented by the use of chemotherapeutic mouthrinses. The authors sought to quantify the additional benefit provided by an essential oil-, or EO-, containing mouthrinse in reducing plaque and gingivitis in patients who brush and floss regularly.

METHODS

The authors randomly assigned patients with gingivitis to one of three treatment groups: brushing and rinsing with a control mouthrinse, or BC; brushing, flossing and rinsing with a control mouthrinse, or BFC; or brushing, flossing and rinsing with an EO-containing mouthrinse, or BFEO. Patients received a dental prophylaxis at baseline, and the authors followed them for six months.

RESULTS

Of 246 enrolled subjects enrolled in the study, 237 subjects were evaluable at the study's conclusion. After six months, the subjects using the BFEO regimen had statistically and clinically significant lower mean Modified Gingival Index, or MGI, scores and Plaque Index, or PI, scores than did subjects in the BC group (29.9 percent and 56.3 percent, respectively; P < .001). Subjects in the BFC group had statistically significantly lower mean MGI and PI scores than did subjects in the BC group (11.2 percent and 9.3 percent, respectively; P < .001). Subjects in the BFEO group exhibited statistically and clinically significantly lower mean scores for MGI and PI than did subjects in the BFC group (21 percent and 51.9 percent, respectively; P < .001).

CONCLUSIONS

This study confirms that for patients with gingivitis who brush and floss routinely, the adjunctive use of an EO-containing mouthrinse provides a clinically significant and meaningful additional benefit in reducing plaque and gingivitis.

CLINICAL IMPLICATIONS

An EO-containing mouthrinse is an effective adjunct to regular brushing and flossing. Therefore, the BFEO regimen can be beneficial for patients with gingival inflammation.

摘要

背景

口腔卫生的机械方法可通过使用化学治疗性漱口水来辅助。作者试图量化含精油(EO)漱口水在减少经常刷牙和使用牙线的患者的牙菌斑和牙龈炎方面所提供的额外益处。

方法

作者将患有牙龈炎的患者随机分配到三个治疗组之一:用对照漱口水刷牙和漱口,即BC组;用对照漱口水刷牙、使用牙线和漱口,即BFC组;或用含EO漱口水刷牙、使用牙线和漱口,即BFEO组。患者在基线时接受了牙齿预防性治疗,作者对他们进行了为期六个月的随访。

结果

在该研究纳入的246名受试者中,237名受试者在研究结束时可进行评估。六个月后,使用BFEO方案的受试者的平均改良牙龈指数(MGI)得分和菌斑指数(PI)得分在统计学和临床上均显著低于BC组受试者(分别为29.9%和56.3%;P < .001)。BFC组受试者的平均MGI和PI得分在统计学上显著低于BC组受试者(分别为11.2%和9.3%;P < .001)。BFEO组受试者的MGI和PI平均得分在统计学和临床上均显著低于BFC组受试者(分别为21%和51.9%;P < .001)。

结论

本研究证实,对于经常刷牙和使用牙线的牙龈炎患者,辅助使用含EO漱口水在减少牙菌斑和牙龈炎方面具有临床上显著且有意义的额外益处。

临床意义

含EO漱口水是常规刷牙和使用牙线的有效辅助手段。因此,BFEO方案对牙龈炎症患者可能有益。

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