Chun Hong H S, Steltenkamp R J, Smith N L
J Pharm Sci. 1975 Dec;64(12):2007-8. doi: 10.1002/jps.2600641225.
Tribromsalan can be quantitatively measured in whole blood and urine by a technique involving extraction with ethyl acetate, treatment with silica gel, separation by TLC, and quantitative measurement by fluorescent spectrophotometry. This method has a sensitivity down to 125 ng (25 ppb in 5.0 ml of sample) of free tribromsalan and shows an average 90% recovery of tribromsalan in blood and urine with standard deviations of 9.7 and 7.4%, respectively.
先用乙酸乙酯萃取，再用硅胶处理，通过薄层色谱法分离，最后用荧光分光光度法定量测量。该方法对游离三溴沙仑的检测灵敏度低至125纳克（在5.0毫升样品中为25 ppb），在血液和尿液中三溴沙仑的平均回收率为90%，标准偏差分别为9.7%和7.4%。
