Barrio E, Calvo M T, Romo A, Alvarez R, Gutiérrez J I, Naval J, Ferrández Longás A
Department of Molecular Genetics, University Children's Hospital Miguel Servet, Zaragoza, Spain.
J Pediatr Endocrinol Metab. 2004 Mar;17 Suppl 3:451-6.
We studied the rate of apoptosis in the placental tissue of pregnancies complicated with intrauterine growth retardation (IUGR) and compared it with the results obtained in normal placentas. Our results clearly demonstrate a strongly increased rate of apoptosis in placentas of children born with IUGR, suggesting severe placental dysfunction. The significance of these findings needs further study.
我们研究了合并宫内生长受限（IUGR）的妊娠胎盘组织中的细胞凋亡率，并将其与正常胎盘的结果进行了比较。我们的结果清楚地表明，出生时患有IUGR的儿童的胎盘细胞凋亡率大幅增加，提示严重的胎盘功能障碍。这些发现的意义需要进一步研究。
