Huber Steven C, Hardin Shane C
United States Department of Agriculture-Agricultural Research Service, Photosynthesis Research Unit and Department of Plant Biology, University of Illinois, Urbana, Illinois 61801, USA.
Curr Opin Plant Biol. 2004 Jun;7(3):318-22. doi: 10.1016/j.pbi.2004.03.002.
The metabolic plasticity displayed by plants during normal development, and in response to environmental fluctuations and stressors, is essential for their growth and survival. The capacity to regulate metabolic enzymes intricately arises in part from posttranslational modifications that can affect enzymatic activity, intracellular localization, protein-protein interactions, and stability. Protein phosphorylation and thiol/disulfide redox modulation are important modifications in plants, and it is likely that O-glycosylation and S-nitrosylation will also emerge as important mechanisms. Recent advances in the field of proteomics, in particular the development of novel and specific chemistries for the detection of a diverse number of modifications, are rapidly expanding our awareness of possible modifications and our understanding of the enzymes whose functions are likely to be regulated posttranslationally.
植物在正常发育过程中以及对环境波动和应激源做出反应时所表现出的代谢可塑性，对其生长和存活至关重要。精细调节代谢酶的能力部分源于可影响酶活性、细胞内定位、蛋白质-蛋白质相互作用和稳定性的翻译后修饰。蛋白质磷酸化和硫醇/二硫键氧化还原调节是植物中的重要修饰，并且O-糖基化和S-亚硝基化也可能成为重要机制。蛋白质组学领域的最新进展，特别是用于检测多种修饰的新型特异性化学方法的开发，正在迅速扩展我们对可能修饰的认识以及对其功能可能在翻译后受到调节的酶的理解。
