小窝蛋白-1在人类肺癌中表达下调，并作为一种候选肿瘤抑制基因发挥作用。 - Suppr

Caveolin-1 is down-regulated in human lung carcinoma and acts as a candidate tumor suppressor gene.

作者信息

Bélanger Martin M, Roussel Elise, Couet Jacques

机构信息

Unité de Recherche en Pneumologie, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Centre de Recherche Hôpital Laval, Sainte-Foy, QC, Canada.

出版信息

Chest. 2004 May;125(5 Suppl):106S. doi: 10.1378/chest.125.5_suppl.106s.

DOI:10.1378/chest.125.5_suppl.106s

PMID:15136443

Abstract

摘要

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Caveolin-1 is down-regulated in human lung carcinoma and acts as a candidate tumor suppressor gene.

Chest. 2004 May;125(5 Suppl):106S. doi: 10.1378/chest.125.5_suppl.106s.

Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer.

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Biochem Biophys Res Commun. 1999 Feb 24;255(3):580-6. doi: 10.1006/bbrc.1999.0236.

Caveolin-1 and caveolin-2,together with three bone morphogenetic protein-related genes, may encode novel tumor suppressors down-regulated in sporadic follicular thyroid carcinogenesis.

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引用本文的文献

Construction of a redox-related gene signature for overall survival prediction and immune infiltration in non-small-cell lung cancer.

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Plasma exosomal caveolin-1 predicts Poor Prognosis in Ovarian Cancer.

J Cancer. 2021 Jun 16;12(16):5005-5012. doi: 10.7150/jca.58762. eCollection 2021.

Systemic redox status in lung cancer patients is related to altered glucose metabolism.

PLoS One. 2018 Sep 20;13(9):e0204173. doi: 10.1371/journal.pone.0204173. eCollection 2018.

Nitric oxide promotes cancer cell dedifferentiation by disrupting an Oct4:caveolin-1 complex: A new regulatory mechanism for cancer stem cell formation.

J Biol Chem. 2018 Aug 31;293(35):13534-13552. doi: 10.1074/jbc.RA117.000287. Epub 2018 Jul 9.

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Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands.

PLoS One. 2017 Feb 10;12(2):e0172067. doi: 10.1371/journal.pone.0172067. eCollection 2017.

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Oncol Lett. 2016 Oct;12(4):2371-2374. doi: 10.3892/ol.2016.4963. Epub 2016 Aug 5.

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Caveolin-1 is down-regulated in human lung carcinoma and acts as a candidate tumor suppressor gene.

作者信息

Bélanger Martin M, Roussel Elise, Couet Jacques

机构信息

Unité de Recherche en Pneumologie, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Centre de Recherche Hôpital Laval, Sainte-Foy, QC, Canada.

出版信息

Chest. 2004 May;125(5 Suppl):106S. doi: 10.1378/chest.125.5_suppl.106s.

DOI:10.1378/chest.125.5_suppl.106s

PMID:15136443

Abstract

摘要

相似文献

Caveolin-1 is down-regulated in human lung carcinoma and acts as a candidate tumor suppressor gene.

Chest. 2004 May;125(5 Suppl):106S. doi: 10.1378/chest.125.5_suppl.106s.

Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer.

Cancer Res. 2004 Jun 15;64(12):4277-85. doi: 10.1158/0008-5472.CAN-03-3941.

Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene.

Am J Pathol. 2001 Nov;159(5):1635-43. doi: 10.1016/S0002-9440(10)63010-6.

Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas.

Am J Pathol. 2001 Mar;158(3):833-9. doi: 10.1016/S0002-9440(10)64031-X.

J Proteome Res. 2004 Jul-Aug;3(4):728-35. doi: 10.1021/pr034127+.

Caveolins as tumour markers in lung cancer detected by combined use of cDNA and tissue microarrays.

J Pathol. 2004 May;203(1):584-93. doi: 10.1002/path.1552.

Emerging gene mutation targets in lung cancer.

Clin Adv Hematol Oncol. 2015 Dec;13(12):812-4.

Invited commentary.

Ann Thorac Surg. 2006 Jul;82(1):248. doi: 10.1016/j.athoracsur.2006.02.046.

Reduction of caveolin 1 gene expression in lung carcinoma cell lines.

Biochem Biophys Res Commun. 1999 Feb 24;255(3):580-6. doi: 10.1006/bbrc.1999.0236.

Caveolin-1 and caveolin-2,together with three bone morphogenetic protein-related genes, may encode novel tumor suppressors down-regulated in sporadic follicular thyroid carcinogenesis.

Cancer Res. 2003 Jun 1;63(11):2864-71.

引用本文的文献

Construction of a redox-related gene signature for overall survival prediction and immune infiltration in non-small-cell lung cancer.

Front Mol Biosci. 2022 Aug 16;9:942402. doi: 10.3389/fmolb.2022.942402. eCollection 2022.

Plasma exosomal caveolin-1 predicts Poor Prognosis in Ovarian Cancer.

J Cancer. 2021 Jun 16;12(16):5005-5012. doi: 10.7150/jca.58762. eCollection 2021.

Systemic redox status in lung cancer patients is related to altered glucose metabolism.

PLoS One. 2018 Sep 20;13(9):e0204173. doi: 10.1371/journal.pone.0204173. eCollection 2018.

Nitric oxide promotes cancer cell dedifferentiation by disrupting an Oct4:caveolin-1 complex: A new regulatory mechanism for cancer stem cell formation.

J Biol Chem. 2018 Aug 31;293(35):13534-13552. doi: 10.1074/jbc.RA117.000287. Epub 2018 Jul 9.

Int J Mol Med. 2017 Jul;40(1):21-30. doi: 10.3892/ijmm.2017.2980. Epub 2017 May 9.

Sclareol inhibits cell proliferation and sensitizes cells to the antiproliferative effect of bortezomib via upregulating the tumor suppressor caveolin-1 in cervical cancer cells.

Mol Med Rep. 2017 Jun;15(6):3566-3574. doi: 10.3892/mmr.2017.6480. Epub 2017 Apr 13.

Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands.

PLoS One. 2017 Feb 10;12(2):e0172067. doi: 10.1371/journal.pone.0172067. eCollection 2017.

Caveolin-1 is overexpressed in hypopharyngeal squamous cell carcinoma and correlates with clinical parameters.

Oncol Lett. 2016 Oct;12(4):2371-2374. doi: 10.3892/ol.2016.4963. Epub 2016 Aug 5.

Caveolin-1 overexpression in benign and malignant salivary gland tumors.

Tumour Biol. 2016 Feb;37(2):1863-9. doi: 10.1007/s13277-015-3968-z. Epub 2015 Sep 1.

Changes in mammary caveolin-1 signaling pathways are associated with breast cancer risk in rats exposed to estradiol in utero or during prepuberty.

Horm Mol Biol Clin Investig. 2010 Jun;2(2):227-234. doi: 10.1515/hmbci.2010.031.

Caveolin-1 is down-regulated in human lung carcinoma and acts as a candidate tumor suppressor gene.

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Caveolin-1 is down-regulated in human lung carcinoma and acts as a candidate tumor suppressor gene.

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