Nitkunan T, Leaver R, Patel H R H, Woodhouse C R J
Institute of Urology, UCL London, UK.
BJU Int. 2004 May;93(7):1043-7. doi: 10.1111/j.1464-410X.2004.04778.x.
To assess the long-term results in patients treated using a modified ureterosigmoidostomy (Mainz II).
Between 1994 and 1999, 17 patients had their lower urinary tract reconstructed by a ureterosigmoidostomy, modified by reconfiguring the rectum to make a low-pressure reservoir (Mainz II). All patients were followed on a standard protocol. Data were extracted from the database and from a review of the case-notes. In 12 patients the procedure was with a radical cystectomy for carcinoma. Five had a failed conventional ureterosigmoidostomy for bladder exstrophy and therefore proceeded to a Mainz II. The data on continence and complications were retrieved for a retrospective analysis; the mean (range) follow-up was 6.4 (4-8.6) years.
Ten of those with bladder cancer and one in the revision group were continent. Two patients in the revision group had sufficiently severe nocturnal incontinence to require conversion to a colonic conduit. Seven of the 17 patients had hyperchloraemic acidosis, one had pyelonephritis and one had renal stones. There were no anastomotic neoplasms.
The Mainz II has a good outcome if used as the primary procedure. In patients with an existing ureterosigmoidostomy who are incontinent, detubularization of the rectosigmoid alone is unlikely to restore continence.
评估采用改良输尿管乙状结肠吻合术(美因茨II式)治疗患者的长期疗效。
1994年至1999年间,17例患者接受了输尿管乙状结肠吻合术进行下尿路重建,该手术通过重新构建直肠以形成低压储尿囊进行改良(美因茨II式)。所有患者均按照标准方案进行随访。数据从数据库及病例记录回顾中提取。12例患者因癌接受了根治性膀胱切除术。5例因膀胱外翻导致传统输尿管乙状结肠吻合术失败,因此接受了美因茨II式手术。获取控尿及并发症数据进行回顾性分析;平均(范围)随访时间为6.4(4 - 8.6)年。
膀胱癌患者中有10例及翻修组中有1例实现控尿。翻修组中有2例夜间尿失禁严重,需要改为结肠造瘘术。17例患者中有7例发生高氯性酸中毒,1例发生肾盂肾炎,1例发生肾结石。未出现吻合口肿瘤。
美因茨II式作为初次手术效果良好。对于已有输尿管乙状结肠吻合术且存在尿失禁的患者,仅对直肠乙状结肠进行去管化不太可能恢复控尿。