Jackson Chris, Knott Claire, Skeate Amanda, Birchwood Max
University of Birmingham and Early Intervention Service, Harry Watton House, Aston, UK.
Aust N Z J Psychiatry. 2004 May;38(5):327-33. doi: 10.1080/j.1440-1614.2004.01359.x.
First episode psychosis can be a distressing and traumatic event which has been linked to comorbid symptomatology, including anxiety, depression and PTSD symptoms (intrusions, avoidance, etc.). However, the link between events surrounding a first episode psychosis (i.e. police involvement, admission, use of Mental Health Act, etc.) and PTSD symptoms remains unproven. In the PTSD literature, attention has now turned to the patient's appraisal of the traumatic event as a key mediator. In this study we aim to evaluate the diagnostic status of first episode psychosis as a PTSD-triggering event and to determine the extent to which cognitive factors such as appraisals and coping mechanisms can mediate the expression of PTSD (traumatic) symptomatology.
Approximately 1.5 years after their first episode of psychosis, patients were assessed for traumatic symptoms, conformity to DSM-IV criteria for posttraumatic stress disorder (PTSD), and their appraisals of the traumatic events and coping strategies. Psychotic symptomatology was also measured.
31% of the sample of 35 patients who agreed to participate reported symptoms consistent with a diagnosis of PTSD. Although no relationship was found between PTSD (traumatic) symptoms and potentially traumatic aspects of the first episode (including place of treatment, detention under the MHA etc.), intrusions and avoidance were positively related to retrospective appraisals of stressfulness of the ward (i.e. the more stressful they rated it the greater the number of PTSD symptoms) and the patient's coping style (sealers were less likely to report intrusive re-experiencing but more likely to report avoidance).
The results call into question whether it is possible to make claims for a simple causal link between psychosis and PTSD. Instead patients' appraisals of potentially traumatic events and their coping styles may mediate the traumatic impact of a first episode of psychosis.
首发精神病可能是一个令人痛苦且具有创伤性的事件,它与共病症状有关,包括焦虑、抑郁和创伤后应激障碍(PTSD)症状(侵入性思维、回避等)。然而,首发精神病周围的事件(如警方介入、入院、使用《精神健康法》等)与PTSD症状之间的联系尚未得到证实。在PTSD相关文献中,注意力现已转向患者对创伤事件的评估,认为这是一个关键的中介因素。在本研究中,我们旨在评估首发精神病作为PTSD触发事件的诊断状况,并确定诸如评估和应对机制等认知因素在多大程度上能够介导PTSD(创伤性)症状的表达。
在患者首次出现精神病症状约1.5年后,对其进行创伤症状评估、是否符合DSM-IV创伤后应激障碍(PTSD)标准的评估,以及对创伤事件的评估和应对策略的评估。同时也对精神病症状进行了测量。
在同意参与的35名患者样本中,31%报告的症状符合PTSD诊断。虽然未发现PTSD(创伤性)症状与首发事件的潜在创伤方面(包括治疗地点、根据《精神健康法》被拘留等)之间存在关联,但侵入性思维和回避与对病房压力的回顾性评估呈正相关(即他们对病房压力的评分越高,PTSD症状数量就越多),并且与患者的应对方式有关(封闭型应对者较少报告侵入性的再次体验,但更有可能报告回避)。
这些结果让人质疑是否可以简单地认为精神病与PTSD之间存在因果联系。相反,患者对潜在创伤事件的评估及其应对方式可能介导了首发精神病的创伤影响。