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J Am Acad Psychiatry Law. 2011;39(1):57-64.
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Arch Gen Psychiatry. 2010 Nov;67(11):1114-9. doi: 10.1001/archgenpsychiatry.2010.147.
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Overview and initial validation of two detailed, multidimensional, retrospective measures of substance use: the Lifetime Substance Use Recall (LSUR) and Longitudinal Substance Use Recall for 12 Weeks (LSUR-12) Instruments.两种详细的、多维的、回顾性物质使用测量方法的概述和初步验证:终生物质使用回忆(LSUR)和 12 周纵向物质使用回忆(LSUR-12)工具。
J Psychiatr Res. 2011 Jan;45(1):83-91. doi: 10.1016/j.jpsychires.2010.04.018. Epub 2010 May 20.
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Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence.大麻使用和儿童期创伤呈相加性交互作用,增加青少年出现精神病症状的风险。
Psychol Med. 2010 Oct;40(10):1627-34. doi: 10.1017/S0033291709991966. Epub 2009 Dec 9.
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Trauma exposure and stress-related disorders in inner city primary care patients.城市内初级保健患者中的创伤暴露和与压力相关的障碍。
Gen Hosp Psychiatry. 2009 Nov-Dec;31(6):505-14. doi: 10.1016/j.genhosppsych.2009.05.003. Epub 2009 Jun 9.
6
Health services determinants of the duration of untreated psychosis among African-American first-episode patients.非裔美国首发精神病患者未治疗精神病期的卫生服务决定因素。
Psychiatr Serv. 2009 Nov;60(11):1489-94. doi: 10.1176/ps.2009.60.11.1489.
7
Family-level predictors and correlates of the duration of untreated psychosis in African American first-episode patients.非裔美国首发精神病患者未治疗精神病期的家庭水平预测因子及其相关性。
Schizophr Res. 2009 Dec;115(2-3):338-45. doi: 10.1016/j.schres.2009.09.029. Epub 2009 Oct 14.
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Association of pre-onset cannabis, alcohol, and tobacco use with age at onset of prodrome and age at onset of psychosis in first-episode patients.首发患者发病前大麻、酒精和烟草使用与前驱期发病年龄及精神病发病年龄的关联。
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9
Prevalence and correlates of school drop-out prior to initial treatment of nonaffective psychosis: further evidence suggesting a need for supported education.非情感性精神病初始治疗前辍学的流行率及其相关因素:进一步的证据表明需要提供支持性教育。
Schizophr Res. 2010 Feb;116(2-3):228-33. doi: 10.1016/j.schres.2009.09.006. Epub 2009 Sep 24.
10
Reliability and comparability of psychosis patients' retrospective reports of childhood abuse.精神疾病患者对儿童期虐待的回溯性报告的可靠性和可比性。
Schizophr Bull. 2011 May;37(3):546-53. doi: 10.1093/schbul/sbp103. Epub 2009 Sep 23.

在以非裔美国人为主、社会经济地位低下、住院治疗的首发精神病患者中,童年和青少年期受虐待和创伤经历的临床相关性。

Clinical correlates of maltreatment and traumatic experiences in childhood and adolescence among predominantly African American, socially disadvantaged, hospitalized, first-episode psychosis patients.

机构信息

Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, Atlanta, GA 30322, USA.

出版信息

Psychiatry Res. 2011 Aug 15;188(3):343-9. doi: 10.1016/j.psychres.2011.05.019. Epub 2011 Jun 12.

DOI:10.1016/j.psychres.2011.05.019
PMID:21665293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3146577/
Abstract

Associations among maltreatment and traumatic experiences in childhood and adolescence, later substance use, and subsequent mental health outcomes for individuals with schizophrenia-spectrum disorders have been initially explored in previous studies; however, research on these factors in socially disadvantaged patients with first-episode psychosis is unavailable. This exploratory, correlational analysis examined associations between maltreatment and trauma-related variables (e.g., traumatic experiences, parental harsh discipline, violence exposure) and: social variables (years of education attained and extent of Axis IV psychosocial problems at initial hospitalization), substance abuse (age at initiation of alcohol and cannabis use, as well as estimates of lifetime intake of both), and positive and negative symptom severity. Rates of childhood abuse and traumatic events were remarkably high in the sample. Years of educational attainment and number of Axis IV psychosocial problems were substantially correlated with several domains of childhood abuse/traumatic events. Age at initiation of alcohol and cannabis use, and lifetime alcohol and cannabis intake, were correlated with a number of trauma domains. Whereas positive symptom severity was correlated with four of the trauma variables, negative symptom severity was correlated only with prior emotional neglect. These results provide insights into the relations among childhood traumatic events, substance use, and clinical features of first-episode psychosis, creating hypotheses for future research.

摘要

先前的研究初步探讨了儿童和青少年时期受虐待和创伤经历、随后的物质使用以及精神分裂症谱系障碍患者随后的心理健康结果之间的关联;然而,对于首次出现精神病的社会劣势患者,这些因素的研究尚属空白。本探索性相关性分析检查了虐待和与创伤相关的变量(例如,创伤经历、父母严厉管教、暴力暴露)之间的关联:社会变量(接受教育的年限和初次住院时的轴 IV 心理社会问题的严重程度)、物质滥用(开始使用酒精和大麻的年龄,以及两者的终生摄入量估计),以及阳性和阴性症状的严重程度。在样本中,儿童期受虐待和创伤事件的发生率非常高。受教育年限和轴 IV 心理社会问题的数量与儿童期虐待/创伤事件的多个领域密切相关。酒精和大麻使用的起始年龄以及终生的酒精和大麻摄入量与多个创伤领域相关。阳性症状的严重程度与四个创伤变量相关,而阴性症状的严重程度仅与先前的情感忽视相关。这些结果深入了解了首发精神病中儿童期创伤事件、物质使用和临床特征之间的关系,为未来的研究提供了假设。