8%七氟醚用于儿童单呼吸和双呼吸肺活量吸入诱导的比较。
A comparison between single- and double-breath vital capacity inhalation induction with 8% sevoflurane in children.
作者信息
Ho Kok-Yuen, Chua Wee-Leng, Lim Serene S T, Ng Agnes S B
机构信息
Department of Anaesthesia (Paediatrics), KK Women's and Children's Hospital, Singapore.
出版信息
Paediatr Anaesth. 2004 Jun;14(6):457-61. doi: 10.1111/j.1460-9592.2004.01237.x.
BACKGROUND
This study was conducted to determine if a double-breath (DB) vital capacity (VC) rapid inhalation induction using immediate high-inspired concentration of sevoflurane is as well tolerated as a single-breath (SB) technique and if it results in a shorter induction time.
METHODS
A total of 104 children, ASA I-II, 6 year and above, undergoing elective surgery were randomly assigned to two groups: SB VC inhalation induction or DB VC inhalation induction with 8% sevoflurane in 66% nitrous oxide. The induction time, complications (cough, laryngospasm, breath-hold, movement, salivation) and level of satisfaction were documented.
RESULTS
Induction was significantly faster in the DB group (41 +/- 9 s) compared with the SB group (50 +/- 14 s). DB inhalation induction was associated with fewer complications (15.4%) than the SB technique (50%).
CONCLUSIONS
Double-breath VC inhalation induction with 8% sevoflurane is as well tolerated as a SB technique and results in a faster onset of anaesthesia.
背景
本研究旨在确定使用即刻高吸入浓度七氟醚的双呼吸（DB）肺活量（VC）快速吸入诱导是否与单呼吸（SB）技术具有相同的耐受性，以及其诱导时间是否更短。
方法
总共104例6岁及以上、ASA I-II级择期手术患儿被随机分为两组：使用66%氧化亚氮中8%七氟醚进行SB VC吸入诱导或DB VC吸入诱导。记录诱导时间、并发症（咳嗽、喉痉挛、屏气、体动、流涎）及满意度。
结果
DB组诱导时间（41±9秒）显著快于SB组（50±14秒）。DB吸入诱导的并发症（15.4%）少于SB技术（50%）。
结论
使用8%七氟醚的双呼吸VC吸入诱导与SB技术耐受性相同，且麻醉起效更快。
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