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七氟醚用于小儿吸入诱导:单呼吸肺活量技术与潮气量技术的比较*

Inhalation induction using sevoflurane in children: the single-breath vital capacity technique compared to the tidal volume technique*.

作者信息

Lejus C, Bazin V, Fernandez M, Nguyen J M, Radosevic A, Quere M F, Le Roux C, Le Corre A, Pinaud M

机构信息

Service of Anaesthesiology, Hôtel-Dieu, CHU Nantes, France.

出版信息

Anaesthesia. 2006 Jun;61(6):535-40. doi: 10.1111/j.1365-2044.2006.04661.x.

Abstract

The single-breath vital capacity technique is suitable for inhalation induction of anaesthesia, using sevoflurane in children aged > 5 years. The purpose of this randomised trial was to compare the single breath vital capacity technique with the conventional tidal volume technique. Seventy- three ASA 1 or 2 children were instructed during the pre-operative visit in the vital capacity technique. The main criterion measured was time to loss of the eyelash reflex. Induction was performed using a circle-absorber breathing circuit primed with sevoflurane 7% in 50% nitrous oxide/oxygen with 6 l.min(-1) fresh gas flow. Time required for induction, haemodynamic changes, airway tolerance and side-effects were recorded. The children's opinion on the technique used was scored using a visual analogue scale (0-100) and a Smiley scale (0-10). The time to loss of the eyelash reflex was found to be reduced in the vital capacity group compared to the tidal volume group. The time to central myosis, to achieve bispectral index values 60 and 40, haemodynamic changes, respiratory events and side-effect incidences were similar in both groups. However, we found that the vital capacity technique was preferred by the children to the tidal volume technique.

摘要

单次呼吸肺活量技术适用于5岁以上儿童使用七氟醚进行麻醉诱导。这项随机试验的目的是比较单次呼吸肺活量技术与传统潮气量技术。73名ASA 1或2级的儿童在术前访视时接受了肺活量技术的指导。测量的主要标准是睫毛反射消失时间。诱导采用循环吸收式呼吸回路,预充7%七氟醚、50%氧化亚氮/氧气,新鲜气流速为6 l.min(-1)。记录诱导所需时间、血流动力学变化、气道耐受性和副作用。使用视觉模拟量表(0 - 100)和笑脸量表(0 - 10)对儿童对所用技术的评价进行评分。与潮气量组相比,肺活量组睫毛反射消失时间缩短。两组在瞳孔中央扩大时间、脑电双频指数达到60和40的时间、血流动力学变化、呼吸事件和副作用发生率方面相似。然而,我们发现儿童更喜欢肺活量技术而非潮气量技术。

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