非典型溶血性尿毒症综合征作为急性淋巴细胞白血病诱导化疗的并发症。
Atypical haemolytic uraemic syndrome as a complication of induction chemotherapy for acute lymphoblastic leukaemia.
作者信息
Chandra D, Lawson S, Ramani P
机构信息
Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK.
出版信息
J Clin Pathol. 2004 Jun;57(6):667-9. doi: 10.1136/jcp.2003.013979.
Abstract
This report describes a case of fatal haemolytic uraemic syndrome (HUS) developing in a child with acute lymphoblastic leukaemia (ALL) during induction chemotherapy. The aetiology in this case is uncertain but it may have resulted from treatment with L-asparaginase or vincristine. The possibility of HUS during induction chemotherapy for ALL should be considered early on in the treatment regimen, if clinical signs and symptoms suggest this diagnosis, so that appropriate treatment can be instituted.
摘要
本报告描述了一名急性淋巴细胞白血病（ALL）患儿在诱导化疗期间发生致命性溶血尿毒综合征（HUS）的病例。该病例的病因尚不确定，但可能是由L-天冬酰胺酶或长春新碱治疗引起的。如果临床体征和症状提示该诊断，在ALL诱导化疗期间应尽早考虑HUS的可能性，以便能够采取适当的治疗措施。
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