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急性淋巴细胞白血病之前的溶血性尿毒综合征。

Haemolytic uraemic syndrome preceding acute lymphoblastic leukaemia.

作者信息

Piel Barbara, Brittain Christine, Dixon Alexander

机构信息

Paediatrics Department, Queen Elizabeth Hospital King's Lynn NHS Foundation Trust, King's Lynn, Norfolk, UK.

出版信息

BMJ Case Rep. 2011 Sep 4;2011:bcr0520114285. doi: 10.1136/bcr.05.2011.4285.

Abstract

An 11-year-old girl presented with diarrhoea associated haemolytic uraemic syndrome (HUS) requiring haemodialysis. Four weeks following the resolution of her renal impairment, she was found to have cervical lymphadenopathy alongside deterioration in her renal function. While blood films during her acute illness were indicative of sepsis only, subsequent film revealed a diagnosis of acute lymphoblastic leukaemia (ALL). Thus, this report describes a rare case of diarrhoea associated HUS preceding the diagnosis of ALL, and may represent an unusual presentation of the malignancy.

摘要

一名11岁女孩出现与溶血性尿毒症综合征(HUS)相关的腹泻,需要进行血液透析。在她的肾功能损害得到缓解四周后,发现她有颈部淋巴结病,同时肾功能恶化。虽然她急性病期间的血涂片仅提示败血症,但随后的血涂片显示诊断为急性淋巴细胞白血病(ALL)。因此,本报告描述了一例罕见的在ALL诊断之前出现腹泻相关HUS的病例,可能代表了该恶性肿瘤的一种不寻常表现。

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本文引用的文献

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Cytokines in childhood hemolytic uremic syndrome and thrombotic thrombocytopenic purpura.
Pediatr Nephrol. 1995 Dec;9(6):694-9. doi: 10.1007/BF00868714.

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