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鼻及鼻咽部错构瘤

Hamartomas of the nose and nasopharynx.

作者信息

Graeme-Cook F, Pilch B Z

机构信息

Department of Pathology, Massachusetts General Hospital, Boston 02114.

出版信息

Head Neck. 1992 Jul-Aug;14(4):321-7. doi: 10.1002/hed.2880140413.

Abstract

Hamartomas are easily diagnosed entities when occurring in the lung and gastrointestinal tract. In the nose and nasopharynx, where such lesions are rare, biopsy of a hamartoma containing epithelial proliferation may lead to a misdiagnosis of cancer, with resultant radical and deforming surgery, particularly if they present in adulthood. We encountered three such lesions over 2 years in the Massachusetts Eye Ear Infirmary, and another was retrieved from the recent files. All presented with nonspecific obstructive symptoms of the nose or nasopharynx, and were treated by resection. Follow-up is short, (4 months to 1 year), but in no case has there been recurrence. The clinical diagnosis was malignancy in 2 cases, inflammatory polyp in one.

摘要

错构瘤发生于肺和胃肠道时易于诊断。在鼻腔和鼻咽部,此类病变罕见,含有上皮增生的错构瘤活检可能导致误诊为癌症,进而导致根治性和毁容性手术,尤其是在成年期出现时。在马萨诸塞州眼耳医院的两年时间里,我们遇到了三例这样的病变,另外一例是从近期病例档案中找到的。所有病例均表现为鼻腔或鼻咽部的非特异性阻塞症状,并接受了切除术。随访时间较短(4个月至1年),但无一例复发。2例临床诊断为恶性肿瘤,1例为炎性息肉。

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