Ryan-Harshman Milly, Aldoori Walid
FEAST Enterprises, Oshawa, ON.
Can Fam Physician. 2004 May;50:727-32.
To demonstrate the role of diet in reducing or aggravating risk of duodenal ulcer (DU).
MEDLINE was searched from January 1966 to December 2001 for articles on the relationship between diet and lifestyle and DU using the key words duodenal ulcer and diet, fibre, or lifestyle. Evidence that these factors are associated with DU arose mainly from three case-control and three prospective studies (level II evidence) and from expert opinion (level III evidence).
A high-fibre diet appears to reduce risk of DU; soluble fibre might be associated with reduced risk also. Vitamin A intake is associated with lower risk of DU. Little evidence indicates that fat, type of fat, protein intake, or consumption of alcohol or caffeine affect the etiology of DU.
A high-fibre diet, particularly if the fibre comes from fruit and vegetables, could reduce risk of DU; vitamin A might also be beneficial.
证明饮食在降低或加重十二指肠溃疡(DU)风险中的作用。
检索MEDLINE 1966年1月至2001年12月期间关于饮食、生活方式与十二指肠溃疡关系的文章,关键词为十二指肠溃疡与饮食、纤维或生活方式。这些因素与十二指肠溃疡相关的证据主要来自三项病例对照研究和三项前瞻性研究(二级证据)以及专家意见(三级证据)。
高纤维饮食似乎可降低十二指肠溃疡风险;可溶性纤维可能也与风险降低有关。维生素A摄入量与较低的十二指肠溃疡风险相关。几乎没有证据表明脂肪、脂肪类型、蛋白质摄入量或酒精或咖啡因的摄入会影响十二指肠溃疡的病因。
高纤维饮食,尤其是纤维来自水果和蔬菜的饮食,可降低十二指肠溃疡风险;维生素A可能也有益处。