Song Moon Hee, Kim Myung-Hwan, Lee Sung Koo, Lee Sang Soo, Han Jimin, Seo Dong Wan, Min Young Il, Lee Dong Ki
Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Gastrointest Endosc. 2004 Jun;59(7):901-5. doi: 10.1016/s0016-5107(04)00457-2.
Endoscopic treatment through the minor papilla is well known in patients with pancreas divisum. However, there are few data concerning endoscopic minor papilla interventions in patients without pancreas divisum when access to the main pancreatic duct via the major papilla is technically difficult.
Records for 213 patients without pancreas divisum who, from April 2001 to June 2003, underwent ERCP for various pancreatic diseases were retrospectively reviewed. Patients were included if they had endoscopic interventions via the minor papilla because access through the major papilla was not possible.
Minor papilla papillotomy or fistulotomy with endoscopic interventions was successful in 10 (91%) of 11 patients. Of these 10 patients, 9 had chronic pancreatitis and one had pancreatic ductal leak from previous pancreatic surgery. The reasons for the inability to access the main pancreatic duct to the tail of the gland via the major papilla included a distorted course of the main pancreatic duct (n=5), impacted stone (n=5), and stricture (n=8). In 8 patients, there were two causes. No complication related to the minor papilla interventions was observed in any patient.
Endoscopic minor papilla interventions are technically feasible in patients with pancreatic diseases but not pancreas divisum when access to the main pancreatic duct via the major papilla is not possible.
在胰腺分裂症患者中,经小乳头进行内镜治疗是众所周知的。然而,对于没有胰腺分裂症且经大乳头进入主胰管存在技术困难的患者,关于内镜下小乳头干预的数据很少。
回顾性分析2001年4月至2003年6月期间因各种胰腺疾病接受内镜逆行胰胆管造影(ERCP)的213例无胰腺分裂症患者的记录。如果患者因无法经大乳头进入而通过小乳头进行内镜干预,则纳入研究。
11例患者中有10例(91%)经内镜干预成功进行了小乳头切开术或瘘管切开术。在这10例患者中,9例患有慢性胰腺炎,1例因先前的胰腺手术导致胰管漏。无法经大乳头进入胰腺体尾部主胰管的原因包括主胰管走行扭曲(n = 5)、结石嵌顿(n = 5)和狭窄(n = 8)。8例患者有两种原因。所有患者均未观察到与小乳头干预相关的并发症。
对于患有胰腺疾病但无胰腺分裂症且无法经大乳头进入主胰管的患者,内镜下小乳头干预在技术上是可行的。