McDonald Mark A, Ojaimi Elvis, Favilla Ian
Clin Exp Ophthalmol. 2004 Jun;32(3):336-9. doi: 10.1111/j.1442-9071.2004.00828.x.
Takayasu's arteritis is a rare idiopathic arteriopathy that produces narrowing and eventually closure of affected blood vessels. Ocular symptoms typically occur late in the disease process in those individuals who have severe involvement of the aortic arch and the carotid arteries. Visual loss typically occurs as a result of either systemic hypertension or concomitant ocular hypo-perfusion. We describe an unusual case of Takayasu's arteritis presenting in a child who complained of painful blurred vision. In this individual, no carotid artery disease was identified on vascular imaging and no evidence of impairment of ocular perfusion was demonstrable. Vision loss in this instance was due to anterior uveitis and cystoid maculopathy. These are atypical and rarely described features of Takayasu's arteritis. The patient responded well to anti-inflammatory treatment and his symptoms resolved. The clinical significance of these findings are discussed and the relevant literature reviewed.
高安动脉炎是一种罕见的特发性动脉疾病,可导致受累血管狭窄并最终闭塞。眼部症状通常在疾病过程后期出现,见于那些主动脉弓和颈动脉严重受累的个体。视力丧失通常是由系统性高血压或伴随的眼部灌注不足所致。我们描述了一例不寻常的高安动脉炎病例,该患儿主诉视力模糊伴疼痛。在该患者中,血管成像未发现颈动脉疾病,也未显示出眼部灌注受损的证据。本例视力丧失是由于前葡萄膜炎和黄斑囊样病变。这些是高安动脉炎的非典型且很少被描述的特征。患者对抗炎治疗反应良好,症状得以缓解。本文讨论了这些发现的临床意义并回顾了相关文献。