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约翰内斯堡的药物滥用与重大创伤

Substance abuse and major trauma in Johannesburg.

作者信息

Bowley Douglas M, Rein Paddy, Cherry Raymond, Vellema Jeanine, Snyman Tracy, Boffard Kenneth D

机构信息

Johannesburg Hospital Trauma Unit, Department of Surgery, University of the Witwatersrand, Johannesburg.

出版信息

S Afr J Surg. 2004 Feb;42(1):7-10.

Abstract

INTRODUCTION

The abuse of alcohol and drugs is a major public health problem and intoxication is one of the most important risk factors for violence and other causes of injury. The aim of the current study was to evaluate the prevalence of drug and alcohol use associated with injury in adult trauma patients in an inner city trauma unit in Johannesburg.

METHODS

A cohort of 105 adult trauma patients admitted to our university trauma unit and its allied medicolegal laboratory were studied in order to provide prospective data and enable us to correlate the prevalence and type of substance abuse with the demographics and injury patterns after major trauma.

RESULTS

Forty-five patients required resuscitation at the Johannesburg Hospital Trauma Unit (JHTU) and 60 patients were examined at the Johannesburg Medicolegal Laboratory (JMLL), giving a total of 105 patients. Blood alcohol concentration (BAC) was positive in 59% of the patients. The average BAC in the trauma unit patients was 37 mmol/l (0.17 g/dl), more than three times the legal limit for driving. Of the patients 43.7% were positive for urinary cannabis; women were statistically significantly more likely to have taken cannabis than men (p = 0.039). There was no difference in rates of exposure to cannabis or alcohol in patients who were the victims of interpersonal violence compared with the victims of accidents (p = 0.17). Only 3 patients had taken other drugs of abuse; 2 had taken Mandrax (methaqualone) and 1 amphetamine.

CONCLUSION

Alcohol and cannabis are commonly misused by trauma patients in Johannesburg; the degree of misuse of other drugs appears to be low. Intoxication is a significant risk factor for violence and accidents and the resultant injuries are a massive burden on our society. Doctors have a responsibility to highlight the association between substance misuse and trauma and should also attempt to persuade individual trauma patients to reduce future alcohol consumption.

摘要

引言

酒精和药物滥用是一个重大的公共卫生问题,而中毒是暴力及其他伤害原因的最重要风险因素之一。本研究的目的是评估约翰内斯堡市中心一家创伤中心成年创伤患者中与伤害相关的药物和酒精使用情况。

方法

对入住我校创伤中心及其附属法医学实验室的105名成年创伤患者进行队列研究,以提供前瞻性数据,并使我们能够将药物滥用的患病率和类型与重大创伤后的人口统计学特征及损伤模式相关联。

结果

45名患者在约翰内斯堡医院创伤中心(JHTU)需要复苏,60名患者在约翰内斯堡法医学实验室(JMLL)接受检查,共计105名患者。59%的患者血液酒精浓度(BAC)呈阳性。创伤中心患者的平均BAC为37 mmol/l(0.17 g/dl),超过法定驾驶限制的三倍多。43.7%的患者尿液大麻检测呈阳性;女性服用大麻的可能性在统计学上显著高于男性(p = 0.039)。人际暴力受害者与事故受害者相比,大麻或酒精暴露率没有差异(p = 0.17)。只有3名患者使用过其他滥用药物;2人服用过安眠酮(甲喹酮),1人服用过安非他明。

结论

约翰内斯堡的创伤患者普遍滥用酒精和大麻;其他药物的滥用程度似乎较低。中毒是暴力和事故的重要风险因素,由此导致的伤害给我们的社会带来了巨大负担。医生有责任强调药物滥用与创伤之间的关联,还应尝试说服个体创伤患者减少未来的酒精消费。

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