儿童胸腺异常的颈部表现
Cervical presentations of thymic anomalies in children.
作者信息
Khariwala S S, Nicollas R, Triglia J M, Garabedian E N, Marianowski R, Van Den Abbeele T, April M, Ward R, Koltai P J
机构信息
Department of Otolaryngology and Communicative Disorders- A71, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
出版信息
Int J Pediatr Otorhinolaryngol. 2004 Jul;68(7):909-14. doi: 10.1016/j.ijporl.2004.02.012.
OBJECTIVE
To better define the clinical manifestations, radiologic imaging and the surgical management of cervical thymic lesions in children.
STUDY DESIGN
Multi-center retrospective case review.
METHODS
The charts of all children with pathologically confirmed thymic lesions at six children's hospitals (1990-2002) were reviewed for demographics, physical findings, X-ray findings, operative outcomes and pathology.
RESULTS
There were a total of 15 children, 2 of whom had ectopic cervical thymus and 13 who had thymic cysts. They ranged in age from 1 month to 18 years. Thymic lesions were more common in males. Ectopic cervical thymus was best defined by MRI whereas thymic cyst had a more consistent appearance on CT. All children had successful surgical resection with no recorded complications or recurrences.
CONCLUSIONS
Cervical thymic lesions are rare. Ectopic cervical thymus tends to be found primarily in infants whereas thymic cysts occur in a wider age range. Radiologic imaging is important but is not histologically specific. Definitive diagnosis and cure requires complete surgical excision.
目的
更好地明确儿童颈部胸腺病变的临床表现、影像学表现及外科治疗方法。
研究设计
多中心回顾性病例分析。
方法
回顾了六家儿童医院（1990 - 2002年）所有经病理确诊胸腺病变儿童的病历，内容包括人口统计学资料、体格检查结果、X线检查结果、手术结果及病理情况。
结果
共有15例儿童，其中2例为异位颈部胸腺，13例为胸腺囊肿。年龄范围从1个月至18岁。胸腺病变在男性中更为常见。MRI对异位颈部胸腺的诊断最为准确，而胸腺囊肿在CT上表现更为一致。所有儿童均成功接受手术切除，无并发症或复发记录。
结论
颈部胸腺病变罕见。异位颈部胸腺主要见于婴儿，而胸腺囊肿发病年龄范围更广。影像学检查很重要，但不能进行组织学特异性诊断。明确诊断和治愈需要完整的手术切除。
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