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髋部骨折术后谵妄对预后的影响。

Effect of postoperative delirium on outcome after hip fracture.

作者信息

Edelstein David M, Aharonoff Gina B, Karp Adam, Capla Edward L, Zuckerman Joseph D, Koval Kenneth J

机构信息

Department of Orthopaedic Surgery, Hospital for Joint Diseases, New York, NY 10003, USA.

出版信息

Clin Orthop Relat Res. 2004 May(422):195-200. doi: 10.1097/01.blo.0000128649.59959.0c.

Abstract

Nine-hundred twenty-one community-dwelling patients 65 years of age or older, who sustained an operatively treated hip fracture from July 1, 1987 to June 30, 1998 were followed up for the development of postoperative delirium. The outcomes examined in the current study were postoperative complication rates, in-hospital mortality, hospital length of stay, hospital discharge status, 1-year mortality rate, place of residence, recovery of ambulatory ability, and activities of daily living 1 year after surgery. Forty-seven (5.1%) patients were diagnosed with postoperative delirium. Patients who had delirium develop were more likely to be male, have a history of mild dementia, and have had surgery under general anesthesia. Patients who had postoperative delirium develop had a significantly longer length of hospitalization. They also had significantly higher rates of mortality at 1 year, were less likely to recover their prefracture level of ambulation, and were more likely to show a decline in level of independence in basic activities of daily living at the 1-year followup. There was no difference in the rate of postoperative complications, in-hospital mortality, discharge residence, and recovery of instrumental activities of daily living at 1 year.

摘要

对1987年7月1日至1998年6月30日期间接受手术治疗髋部骨折的921名65岁及以上社区居住患者进行随访,观察术后谵妄的发生情况。本研究考察的结局指标包括术后并发症发生率、住院死亡率、住院时间、出院状态、1年死亡率、居住地点、术后1年行走能力恢复情况以及日常生活活动能力。47名(5.1%)患者被诊断为术后谵妄。发生谵妄的患者更可能为男性,有轻度痴呆病史,且接受过全身麻醉手术。发生术后谵妄的患者住院时间显著更长。他们在1年时的死亡率也显著更高,恢复骨折前行走水平的可能性更小,且在1年随访时基本日常生活活动独立性水平下降的可能性更大。术后并发症发生率、住院死亡率、出院居住情况以及术后1年工具性日常生活活动恢复情况方面无差异。

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