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吉兰丹的高血压及相关心血管危险因素

Hypertension and associated cardiovascular risk factors in Kelantan.

作者信息

Mafauzy M, Mokhtar N, Wan Mohamad W B

机构信息

Department of Medicine, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kota Bharu, Kelantan.

出版信息

Med J Malaysia. 2003 Oct;58(4):556-64.

Abstract

Two thousand five hundred and eight subjects from the state of Kelantan in North-East Peninsular Malaysia were included in this study to determine the prevalence of hypertension and their association with cardiovascular risk factors. The overall prevalence of hypertension was 13.9%. There was no difference in the prevalence of hypertension between the males and females. The prevalence increased with age--the highest being in those above 70-years old. Subjects with hypertension also had a higher prevalence of diabetes mellitus (19.0%), obesity (39.4%) and hypercholesterolaemia (70.7%) than non-hypertensive subjects. Of the hypertensive subjects, 83.3% had 1 other risk factor for cardiovascular disease, 66.7% had 2 other risk factors and 16.7% had more than 2 risk factors. Other than age, body mass index, plasma glucose, total cholesterol and LDL-cholesterol, hypertensive subjects also had a higher mean serum urea, creatinine, uric acid and triglyceride than non-hypertensive subjects. In conclusion, hypertension is a common disease in this area and is associated with multiple risk factors for cardiovascular disease. The prevalence is likely to increase in the near future with increasing affluence and becoming a major health problem.

摘要

本研究纳入了马来西亚半岛东北部吉兰丹州的2508名受试者,以确定高血压的患病率及其与心血管危险因素的关联。高血压的总体患病率为13.9%。男性和女性的高血压患病率没有差异。患病率随年龄增长而增加,最高的是70岁以上的人群。与非高血压受试者相比,高血压受试者患糖尿病(19.0%)、肥胖(39.4%)和高胆固醇血症(70.7%)的患病率也更高。在高血压受试者中,83.3%有1种其他心血管疾病危险因素,66.7%有2种其他危险因素,16.7%有2种以上危险因素。除年龄、体重指数、血糖、总胆固醇和低密度脂蛋白胆固醇外,高血压受试者的平均血清尿素、肌酐、尿酸和甘油三酯也高于非高血压受试者。总之,高血压在该地区是一种常见疾病,并且与多种心血管疾病危险因素相关。随着财富的增加,患病率在不久的将来可能会上升,并成为一个主要的健康问题。

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