甲状腺微小乳头状癌：包括组织学亚型在内的预后因素分析

Papillary microcarcinoma of the thyroid gland: analysis of prognostic factors including histological subtype.

作者信息

Falvo Laura, D'Ercole Claudia, Sorrenti Salvatore, D'Andrea Vito, Catania Antonio, Berni Alberto, Grilli Paola, De Antoni Enrico

机构信息

Division of General Surgery, Department of Surgical Sciences, "La Sapienza" University of Rome, Rome, Italy.

出版信息

Eur J Surg Suppl. 2003 Jul(588):28-32.

OBJECTIVE

To evaluate the prognosis of papillary microcarcinoma (PMC) of the thyroid.

DESIGN

Prospective study.

SETTING

Teaching hospital, Italy.

SUBJECTS

89 patients treated for papillary micro carcinoma of thyroid and followed up for at least 6 years (range 6-12).

INTERVENTION

Total thyroidectomy and, for lymph node metastases, laterocervical lymphadenectomy.

MAIN OUTCOME MEASURES

Sex distribution, mode of onset of disease, diameter of tumour, histological type, histological stage, presence of lymph node metastases at the time of operation and type of operation.

RESULTS

When the disease presented with laterocervical lymph nodes it was histologically more aggressive and included follicular (n = 3) and sclerosing (n = 4) types.

CONCLUSION

Papillary microcarcinoma has an excellent prognosis if managed initially by total thyroidectomy.

目的

评估甲状腺微小乳头状癌（PMC）的预后。

设计

前瞻性研究。

地点

意大利的教学医院。

研究对象

89例接受甲状腺微小乳头状癌治疗且随访至少6年（6 - 12年）的患者。

干预措施

全甲状腺切除术，对于有淋巴结转移的患者，行颈侧区淋巴结清扫术。

主要观察指标

性别分布、疾病发病方式、肿瘤直径、组织学类型、组织学分期、手术时淋巴结转移情况及手术类型。

结果

当疾病伴有颈侧区淋巴结时，其组织学上更具侵袭性，包括滤泡型（n = 3）和硬化型（n = 4）。

结论

如果最初通过全甲状腺切除术进行治疗，甲状腺微小乳头状癌的预后良好。