Synthesis of omega-hydroxy ketones from omega-benzyloxy Weinreb amides by using a chemoselective nucleophilic addition/Birch reduction process.

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作者信息

Taillier Catherine, Bellosta Véronique, Meyer Christophe, Cossy Janine

机构信息

Laboratoire de Chimie Organique, associé au CNRS, 10 rue Vauquelin, 75231 Paris Cedex 05, France.

出版信息

Org Lett. 2004 Jun 24;6(13):2145-7. doi: 10.1021/ol049434f.

DOI:10.1021/ol049434f

PMID:15200306

Abstract

[reaction: see text] A chemoselective nucleophilic addition/Birch reduction process applied to omega-benzyloxy Weinreb amides led to omega-hydroxy ketones in good yields.

摘要

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