Santolaria Piedrafita S, Conde García R, Abascal Agorreta M, Domínguez Torres I, Ducóns García J, Guirao Larrañaga R, Montoro Huguet M
Sección de Aparato Digestivo, Hospital San Jorge, Huesca, Spain.
Gastroenterol Hepatol. 2004 Jun-Jul;27(6):357-61. doi: 10.1157/13062890.
Ménétrier's disease is an infrequent clinical entity characterized by thickening of the gastric folds secondary to hyperplasia of the foveolar mucosa cells, frequently associated with loss of enteric proteins and hypoalbuminemia. Its etiology is unknown, although in the last few years it has been related to Helicobacter pylori infection. We present the case of a 38-year-old man with protein-losing gastroenteropathy caused by Ménétrier's disease, in whom eradication of H. pylori infection was followed by symptom improvement and resolution of hypoalbuminemia. In agreement with the criteria of other authors, we investigate the presence of H. pylori infection in all patients with Ménétrier's disease. When positive, the first-line treatment consists of eradication therapy.
梅内特里耶病是一种罕见的临床病症,其特征为胃皱襞增厚,继发于小凹黏膜细胞增生,常伴有肠蛋白丢失和低蛋白血症。其病因不明,尽管在过去几年中已发现它与幽门螺杆菌感染有关。我们报告一例由梅内特里耶病引起的蛋白丢失性胃肠病的38岁男性病例,该患者根除幽门螺杆菌感染后症状改善且低蛋白血症得到缓解。根据其他作者的标准,我们对所有梅内特里耶病患者进行幽门螺杆菌感染检测。若检测结果为阳性,一线治疗方案为根除治疗。