Izak Andrea M, Werner Liliana, Pandey Suresh K, Apple David J
David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, 50 North Medical Drive, Salt Lake City, UT 84132, USA.
J Cataract Refract Surg. 2004 Jul;30(7):1537-44. doi: 10.1016/j.jcrs.2003.11.047.
To report the pathological findings in 14 human cadaver eyes implanted with a single-piece AcrySof(Alcon Laboratories) posterior chamber intraocular lens (IOL).
David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.
Fourteen human autopsy eyes implanted with a single-piece AcrySof (SA30AL) IOL were evaluated. The eyes were sectioned at the equatorial plane, and the anterior segment containing the IOL in the capsular bag was evaluated from a posterior perspective (Miyake-Apple view) and from an anterior perspective (surgeon's view) after removal of cornea and iris. They were then processed through paraffin, sectioned, and stained with hematoxylin-eosin, periodic acid-Schiff, and Masson's trichrome and examined under light microscopy.
All IOLs had symmetric in-the-bag fixation. Slight decentration was measured in 1 eye, which also had an anterior capsule tear. Grade 1 anterior capsule opacification was present in 9 eyes. No central posterior capsule opacification or posterior capsule folds were observed in any eye. Soemmering's ring formation was observed in 5 eyes. Zonular stretch caused by different degrees of capsular bag contraction was present in 4 eyes without decentration of the IOL.
Analyses of pseudophakic cadaver eyes from the posterior (Miyake-Apple) view, complemented by microscopic analyses, proved useful in the evaluation of IOL-capsular bag interaction. These studies are more important in cases of newly introduced lens designs.
报告14只植入单片式AcrySof（爱尔康实验室）后房型人工晶状体（IOL）的人类尸体眼的病理检查结果。
美国犹他州盐湖城犹他大学约翰·A·莫兰眼科中心大卫·J·阿普尔医学博士眼科设备研究实验室。
对14只植入单片式AcrySof（SA30AL）IOL的人类尸检眼进行评估。在赤道平面剖切眼球，在去除角膜和虹膜后，从后视角（三宅-阿普尔视图）和前视角（术者视图）评估囊袋内包含IOL的前段。然后将其进行石蜡包埋、切片，并用苏木精-伊红、过碘酸-希夫和马森三色染色，在光学显微镜下检查。
所有IOL均在囊袋内固定对称。1只眼测量有轻微偏心，该眼同时存在前囊膜撕裂。9只眼出现1级前囊膜混浊。所有眼中均未观察到中央后囊膜混浊或后囊膜皱襞。5只眼观察到Soemmering环形成。4只眼存在不同程度囊袋收缩导致的悬韧带伸展，但IOL未偏心。
从后视角（三宅-阿普尔视图）分析假晶状体尸体眼，并辅以显微镜分析，被证明有助于评估IOL与囊袋的相互作用。这些研究在新引入的晶状体设计的情况下更为重要。
