Joshi Rajesh Subhash
Department of Ophthalmology, Shri Vasantrao Government Medical College, Yavatmal, Maharashtra, India.
Indian J Ophthalmol. 2017 Jun;65(6):466-471. doi: 10.4103/ijo.IJO_344_16.
To evaluate the incidence of postoperative posterior capsular striae (PCS) and its influence on posterior capsular opacification (PCO) in patients implanted with two types of lens material.
Tertiary eye care center in central rural India.
A prospective, observational, nonrandomized study.
The study included 1247 patients having age-related cataract scheduled for removal by phacoemulsification technique and implantation of hydrophilic or hydrophobic intraocular lens (IOL). Demographic profile, nuclear grading, axial length, and IOL power were noted. Details of PCS were noted on the 1st postoperative day in patients with clear cornea. Postoperative follow-up was ensured to study the status of PCS and development of PCO.
The overall incidence of PCS was 19.8% (247 out of 1247 eyes). Out of 1247 patients, 641 patients (51.4%) had hydrophilic IOL implantation and 201 eyes had PCS (31.4%) and 606 patients (48.6%) had hydrophobic IOL implantation and 46 eyes had PCS (7.6%), P = 0.04. Three and more striae were seen in 119 eyes (119/641, 18.6%) in hydrophilic group and 4 eyes (4/606, 0.66%) in hydrophobic group. Sixty-two eyes (62/201, 30.9%) in hydrophilic group with multiple PCS were reported with persistent striae after 6 months of surgery. Two eyes in hydrophobic group had persistent striae even after 3 years of follow-up. Evaluation of PCO score of the hydrophilic group was 0.6 whereas of the hydrophobic group was 0.1 (P = 0.04). Ten patients of the hydrophilic group only required neodymium-doped yttrium aluminum garnet (ND: YAG) laser capsulotomy.
The incidence of PCS was higher in hydrophilic than hydrophobic IOLs. Multiple PCS persisting in patients beyond 6 months after operation should be followed up for early development of PCO, particularly in patients implanted with hydrophilic IOL.
评估植入两种类型晶状体材料的患者术后后囊膜条纹(PCS)的发生率及其对后囊膜混浊(PCO)的影响。
印度中部农村地区的三级眼科护理中心。
一项前瞻性、观察性、非随机研究。
该研究纳入了1247例患有年龄相关性白内障且计划通过超声乳化技术摘除并植入亲水性或疏水性人工晶状体(IOL)的患者。记录人口统计学资料、核分级、眼轴长度和IOL屈光度。在角膜透明的患者术后第1天记录PCS的详细情况。确保进行术后随访以研究PCS的状态和PCO的发生情况。
PCS的总体发生率为19.8%(1247只眼中的247只)。在1247例患者中,641例(51.4%)植入了亲水性IOL,其中201只眼出现PCS(31.4%);606例(48.6%)植入了疏水性IOL,其中46只眼出现PCS(7.6%),P = 0.04。亲水性组119只眼(119/641,18.6%)出现三条及以上条纹,疏水性组4只眼(4/606,0.66%)出现三条及以上条纹。亲水性组中62只眼(62/201,30.9%)有多条PCS,术后6个月仍有持续条纹。疏水性组中有2只眼即使在随访3年后仍有持续条纹。亲水性组的PCO评分为0.6,而疏水性组为0.1(P = 0.04)。仅10例亲水性组患者需要钕掺杂钇铝石榴石(ND:YAG)激光囊膜切开术。
亲水性IOL植入患者的PCS发生率高于疏水性IOL。术后6个月以上患者持续存在多条PCS应随访观察PCO的早期发生情况,尤其是植入亲水性IOL的患者。