Minami Koichi, Yanagawa Toshihiko, Okuda Masumi, Suzuki Hiroyuki, Tamura Akira, Izumi Genkichi, Yoshikawa Norishige
Department of Pediatrics, Wakayama Medical University School of Medicine, Wakayama 641-0012, Japan.
Tohoku J Exp Med. 2004 Jun;203(2):129-32. doi: 10.1620/tjem.203.129.
We present a case report of encephalopathy associated with Salmonella urbana infection in a child. A 5-year-old boy was admitted to our clinic with convulsions and coma. Cerebrospinal fluid (CSF) interleukin-6 (IL-6) and IL-8 were elevated at onset and were decreased within normal limit on the fifth day. Residual neurological deficits included severe mental deficits and spastic tetraplegia. High levels of CSF proinflammatory cytokines might be related to central nervous system (CNS) disease activity. Although encephalopathy is a rare complication of non-typhi Salmonella infection, it should be borne in mind as an occasionally serious and potentially lethal disease.
我们报告一例儿童中与城市沙门氏菌感染相关的脑病病例。一名5岁男孩因惊厥和昏迷入住我们的诊所。脑脊液（CSF）白细胞介素-6（IL-6）和IL-8在发病时升高，并在第五天降至正常范围。残留的神经功能缺损包括严重智力缺陷和痉挛性四肢瘫。脑脊液促炎细胞因子水平升高可能与中枢神经系统（CNS）疾病活动有关。尽管脑病是非伤寒沙门氏菌感染的罕见并发症，但应将其视为一种偶尔严重且可能致命的疾病。
