自我报告与其他药物依从性测量方法的一致性：文献综述

The concordance of self-report with other measures of medication adherence: a summary of the literature.

作者信息

Garber Mathew C, Nau David P, Erickson Steven R, Aikens James E, Lawrence Joseph B

机构信息

Social and Administrative Sciences, University of Michigan College of Pharmacy, Ann Arbor, Michigan 48109-1065, USA.

出版信息

Med Care. 2004 Jul;42(7):649-52. doi: 10.1097/01.mlr.0000129496.05898.02.

DOI:10.1097/01.mlr.0000129496.05898.02

PMID:15213489

Abstract

OBJECTIVE

The objective of this study was to evaluate the concordance of self-report measures of medication adherence (interview, diary, or questionnaire) with nonself-report measures of adherence (administrative claims, pill count or canister weight, plasma drug concentration, electronic monitors, or clinical opinion).

METHODS

A literature search was conducted to identify published reports in which self-report and nonself-report measures of adherence were used within the same study. The concordance of measures within each study was categorized as high, moderate, or low based on a comparison of the adherence estimates.

RESULTS

Eight-six comparisons of self-report to nonself-report measures of adherence were identified. Thirty-seven of the 86 comparisons (43%) were categorized as highly concordant. However, concordance varied substantially by type of self-report measure and nonself-report measure. Self-report measures, in general, were highly concordant with electronic measures in only 17% of comparisons, whereas they were highly concordant with other types of nonself-report measures in 58% of comparisons (chi-square = 14.30, P <0.01). When comparing self-report measures, interviews had significantly lower concordance with nonself-report measures as compared with questionnaires or diaries (chi-square = 8.47, P = 0.01). In 15 comparisons of interviews with electronic measures, none of the comparisons were highly concordant, whereas questionnaires and diaries had moderate-to-high concordance with electronic measures in 12 of 16 comparisons (75%).

CONCLUSIONS

The concordance of self-report and other measures of medication adherence varies widely based on the type of measures used. Questionnaires and diaries tend to have moderate-to-high concordance with other measures of medication adherence. However, interview-based self-reports are not concordant with electronic measures. Questionnaire and diary methods could be preferable to interviews for self-reported medication adherence.

摘要

目的

本研究的目的是评估药物依从性的自我报告测量方法（访谈、日记或问卷）与非自我报告测量方法（行政索赔、药丸计数或药罐重量、血浆药物浓度、电子监测器或临床意见）之间的一致性。

方法

进行文献检索，以识别在同一研究中使用自我报告和非自我报告依从性测量方法的已发表报告。根据依从性估计值的比较，将每项研究中测量方法的一致性分为高、中或低。

结果

确定了86项自我报告与非自我报告依从性测量方法的比较。86项比较中的37项（43%）被归类为高度一致。然而，一致性因自我报告测量方法和非自我报告测量方法的类型而有很大差异。一般来说，自我报告测量方法在仅17%的比较中与电子测量方法高度一致，而在58%的比较中与其他类型的非自我报告测量方法高度一致（卡方 = 14.30，P <0.01）。在比较自我报告测量方法时，与问卷或日记相比，访谈与非自我报告测量方法的一致性显著较低（卡方 = 8.47，P = 0.01）。在15项访谈与电子测量方法的比较中，没有一项比较是高度一致的，而在16项比较中的12项（75%）中，问卷和日记与电子测量方法有中度至高度的一致性。