Martin R J
University of Colorado Health Sciences Center, Denver.
Clin Chest Med. 1992 Sep;13(3):533-50.
The nocturnal worsening of asthma is a common problem that can have significant related morbidity and mortality. There are many circadian biologic rhythms that contribute to the increased nocturnal bronchial reactivity and decrement in lung function. Therapy directed at the nocturnal aspect of this asthma process can produce marked improvement in symptoms and lung function.
哮喘的夜间病情加重是一个常见问题，可导致显著的相关发病率和死亡率。有许多昼夜生物节律导致夜间支气管反应性增加和肺功能下降。针对哮喘这一夜间过程的治疗可使症状和肺功能得到显著改善。
