D'Ambrosio C M, Mohsenin V
Department of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Clin Chest Med. 1998 Mar;19(1):127-37. doi: 10.1016/s0272-5231(05)70437-8.
The nocturnal worsening of asthma is a major cause of morbidity and mortality from this disease. The physiologic changes that occur during normal sleep can have adverse effects on breathing patterns, arousal responses, and airway clearance in asthmatics. Understanding of these alterations in airway mechanics and airway inflammation may lead to better management of this disease.
哮喘的夜间病情加重是该疾病发病和死亡的主要原因。正常睡眠期间发生的生理变化可能会对哮喘患者的呼吸模式、觉醒反应和气道清除产生不利影响。了解气道力学和气道炎症的这些改变可能会改善对该疾病的管理。
