Vazquez Mata G, Rivera Fernandez R, Gonzalez Carmona A, Delgado-Rodriguez M, Torres Ruiz J M, Raya Pugnaire A, Aguayo de Hoyos E
Intensive Care Unit, General Hospital Virgen de la Nieves, Granada, Spain.
Crit Care Med. 1992 Sep;20(9):1257-62. doi: 10.1097/00003246-199209000-00012.
To perform an analysis of the quality of life of survivors after ICU discharge.
Prospective study.
Medical-surgical ICU of a Spanish reference hospital.
Patients (n = 606) admitted in a 6-month period.
A questionnaire regarding quality of life issues was completed at the time of admission by patients or surrogates (n = 606). The questionnaire was given again 12 months after ICU discharge to 444 surviving patients. Both questionnaires evaluated the patient's ability to function and communicate for the previous 3 months. A Quality of Life score of 0 corresponded to no limitations. An increasing score indicated a reduction in function. A score of greater than 10 points implied a severe physical handicap. Information was also collected on the severity of illness and the diagnosis that prompted ICU admission.
The mean Quality of Life score of all survivors worsened from a mean of 4.62 at the time of ICU admission to a mean of 6.11 at 12 months after ICU discharge (p less than .01) and was most evident for patients greater than 75 yrs of age (from a mean of 6.33 to a mean of 9.54). However, patients with the highest initial Quality of Life scores had a significant improvement at 12 months (14.61 +/- 0.50 to 12.48 +/- 0.78 points [p less than .05]). A higher severity of illness score corresponded to a higher Quality of Life score, but a multivariate analysis indicated that the factors with the greatest influence on the post-discharge Quality of Life score were the initial Quality of Life score and age.
Twelve months after discharge from the ICU, a patient's functional status, as measured by the Quality of Life score, is influenced most by age and their Quality of Life score at the time of ICU admission. While there is an overall decrease in the Quality of Life score for survivors, admission and treatment in an ICU do not always result in deterioration of the Quality of Life score. This study indicates that Quality of Life scores could become a routine part of patient evaluation.
对重症监护病房(ICU)出院后的幸存者生活质量进行分析。
前瞻性研究。
西班牙一家参考医院的内科-外科重症监护病房。
6个月内收治的患者(n = 606)。
患者或其代理人(n = 606)在入院时填写一份关于生活质量问题的问卷。ICU出院12个月后,对444名存活患者再次发放问卷。两份问卷均评估患者在前3个月的功能和沟通能力。生活质量评分为0表示无限制。分数增加表明功能下降。得分超过10分意味着严重身体残疾。还收集了疾病严重程度及促使患者入住ICU的诊断信息。
所有幸存者的平均生活质量评分从ICU入院时的4.62分恶化至ICU出院12个月后的6.11分(p < 0.01),在75岁以上患者中最为明显(从平均6.33分至平均9.54分)。然而,初始生活质量评分最高的患者在12个月时有显著改善(从14.61 ± 0.50分至12.48 ± 0.78分 [p < 0.05])。疾病严重程度评分越高对应生活质量评分越高,但多因素分析表明,对出院后生活质量评分影响最大的因素是初始生活质量评分和年龄。
ICU出院12个月后,用生活质量评分衡量的患者功能状态受年龄及ICU入院时生活质量评分影响最大。虽然幸存者的生活质量评分总体下降,但在ICU的入院和治疗并不总是导致生活质量评分恶化。本研究表明,生活质量评分可成为患者评估的常规部分。