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Ultrathin-wall, two-stage, twin endotracheal tube: a tracheal tube with minimal resistance and minimal dead space for use in newborn and infant patients.

作者信息

Kolobow Theodor, Berra Lorenzo, DeMarchi Lorenzo, Aly Hany

机构信息

Pulmonary-Critical Care Medicine Branch, Section of Pulmonary and Cardiac Assist Devices, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-1434, USA.

出版信息

Pediatr Crit Care Med. 2004 Jul;5(4):379-83. doi: 10.1097/01.pcc.0000128602.22489.2d.

DOI:10.1097/01.pcc.0000128602.22489.2d
PMID:15215010
Abstract

OBJECTIVE

To design and fabricate crush-proof polyurethane tracheal tubes for the newborn with the lowest resistance, least dead space, and thinnest wall.

DESIGN

Test and evaluation of a novel, low-resistance, and low-dead-space tracheal tube for newborns.

SETTING

National Institutes of Health Research Laboratory.

INTERVENTIONS

The short orotracheal portion of the tracheal tube was fabricated of polyurethane, reinforced with flat nickel-titanium shape-memory alloy (Nitinol) to render the tube crush-proof, of a wall thickness about one half of a standard tracheal tube. To the oral part of the tracheal tube, which is the sole dead-space, we attached a Y piece. We connected to one arm of the Y a nonreinforced (inspiratory) tube of larger internal diameter, and a similar tube (expiratory) to the other.

MEASUREMENTS AND RESULTS

The computed air flow resistance, as derived from the pressure/flow curves, is about one half to one third the resistance of a comparable standard tracheal tube at flow rates up to 8 L/min, with a tubing, connector, and adapter dead space three to seven times smaller, depending on the tracheal tube connector piece, the ventilator tube connector piece, and size of the tracheal tube.

CONCLUSIONS

The novel tracheal tube design has a resistance to gas flow one half to one third that of a standard tracheal tube and a dead-space volume three to seven times lower, including tubing and connector dead space. In addition, it offers a means for potential accurate, continuous online monitoring of expiratory oxygen and Co(2) concentration and gas flow, in both the inspiratory and the expiratory lines, without contributing to dead-space ventilation or gas flow resistance.

摘要

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"Treating Lungs": The Scientific Contributions of Dr. Theodor Kolobow.“治疗肺部”:西奥多·科洛博夫博士的科学贡献
ASAIO J. 2016 Mar-Apr;62(2):203-10. doi: 10.1097/MAT.0000000000000323.
2
Dead space reduction by Kolobow's endotracheal tube does not justify the waiving of volume monitoring in small, ventilated lungs.科洛博气管导管减少无效腔并不能成为在小容量通气肺中放弃容量监测的理由。
J Clin Monit Comput. 2014 Dec;28(6):605-11. doi: 10.1007/s10877-014-9559-5. Epub 2014 Jan 28.