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Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries.来自10个中东欧国家的1011株化脓性链球菌对泰利霉素的敏感性。
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韩国β-溶血性链球菌的抗菌药物敏感性模式及大环内酯类耐药基因

Antimicrobial susceptibility patterns and macrolide resistance genes of beta-hemolytic streptococci in Korea.

作者信息

Uh Young, Jang In Ho, Hwang Gyu Yel, Lee Mi Kyung, Yoon Kap Jun, Kim Hyo Youl

机构信息

Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Ilsan-dong 162, Wonju, Kangwon-do, South Korea.

出版信息

Antimicrob Agents Chemother. 2004 Jul;48(7):2716-8. doi: 10.1128/AAC.48.7.2716-2718.2004.

DOI:10.1128/AAC.48.7.2716-2718.2004
PMID:15215133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC434227/
Abstract

In 540 beta-hemolytic streptococci, the rates of resistance to tetracycline, chloramphenicol, erythromycin, and clindamycin were 80.0, 22.8, 20.2, and 19.1%, respectively. Of the erythromycin-resistant isolates, 63.3% had the constitutive macrolide-lincosamide-streptogramin B (MLS(B)) resistance phenotype, 23.9% had the M phenotype, and 12.8% had the inducible MLS(B) resistance phenotype. The constitutive MLS(B) resistance phenotype with the erm(B) gene was dominant in Korea.

摘要

在540株β-溶血性链球菌中,对四环素、氯霉素、红霉素和克林霉素的耐药率分别为80.0%、22.8%、20.2%和19.1%。在红霉素耐药菌株中,63.3%具有组成型大环内酯-林可酰胺-链阳菌素B(MLS(B))耐药表型,23.9%具有M表型,12.8%具有诱导型MLS(B)耐药表型。带有erm(B)基因的组成型MLS(B)耐药表型在韩国占主导地位。