Ruan Jianhua, Stormo Gary D, Zhang Weixiong
Department of Computer Science and Engineering, Washington University in St Louis, St Louis, MO 63130, USA.
Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W146-9. doi: 10.1093/nar/gkh444.
The ILM web server provides a web interface to two algorithms, iterated loop matching and maximum weighted matching, for efficiently predicting RNA secondary structures with pseudoknots. The algorithms can utilize either thermodynamic or comparative information or both, and thus can work on both aligned and individual sequences. Predicted secondary structures are presented in several formats compatible with a variety of existing visualization tools. The service can be accessed at http://cic.cs.wustl.edu/RNA/.
ILM网络服务器提供了一个网络界面,可用于两种算法,即迭代循环匹配和最大加权匹配,以高效预测带有假结的RNA二级结构。这些算法可以利用热力学信息或比较信息,也可以同时利用两者,因此可以处理比对序列和单个序列。预测的二级结构以多种格式呈现,与各种现有的可视化工具兼容。可通过http://cic.cs.wustl.edu/RNA/访问该服务。