GOblet：一个用于对匿名序列数据进行基因本体注释的平台。
GOblet: a platform for Gene Ontology annotation of anonymous sequence data.
作者信息
Groth Detlef, Lehrach Hans, Hennig Steffen
机构信息
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany.
出版信息
Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W313-7. doi: 10.1093/nar/gkh406.
Abstract
GOblet is a comprehensive web server application providing the annotation of anonymous sequence data with Gene Ontology (GO) terms. It uses a variety of different protein databases (human, murines, invertebrates, plants, sp-trembl) and their respective GO mappings. The user selects the appropriate database and alignment threshold and thereafter submits single or multiple nucleotide or protein sequences. Results are shown in different ways, e.g. as survey statistics for the main GO categories for all sequences or as detailed results for each single sequence that has been submitted. In its newest version, GOblet allows the batch submission of sequences and provides an improved display of results with the aid of Java applets. All output data, together with the Java applet, are packed to a downloadable archive for local installation and analysis. GOblet can be accessed freely at http://goblet.molgen.mpg.de.
摘要
GOblet是一个综合的网络服务器应用程序，可使用基因本体（GO）术语对匿名序列数据进行注释。它使用各种不同的蛋白质数据库（人类、小鼠、无脊椎动物、植物、sp-trembl）及其各自的GO映射。用户选择合适的数据库和比对阈值，然后提交单条或多条核苷酸或蛋白质序列。结果以不同方式显示，例如作为所有序列主要GO类别的调查统计数据，或作为每条提交的单条序列的详细结果。在其最新版本中，GOblet允许批量提交序列，并借助Java小程序改进结果显示。所有输出数据与Java小程序一起打包成可下载的存档文件，用于本地安装和分析。可通过http://goblet.molgen.mpg.de免费访问GOblet。
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