SCit：用于蛋白质侧链构象分析的网络工具。
SCit: web tools for protein side chain conformation analysis.
作者信息
Gautier R, Camproux A-C, Tufféry P
机构信息
Equipe de Bioinformatique Génomique et Moléculaire, INSERM E346, Université Paris 7, case 7113, 2, place Jussieu, 75251 Paris cedex 05, France.
出版信息
Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W508-11. doi: 10.1093/nar/gkh388.
Abstract
SCit is a web server providing services for protein side chain conformation analysis and side chain positioning. Specific services use the dependence of the side chain conformations on the local backbone conformation, which is described using a structural alphabet that describes the conformation of fragments of four-residue length in a limited library of structural prototypes. Based on this concept, SCit uses sets of rotameric conformations dependent on the local backbone conformation of each protein for side chain positioning and the identification of side chains with unlikely conformations. The SCit web server is accessible at http://bioserv.rpbs.jussieu.fr/SCit.
摘要
SCit是一个为蛋白质侧链构象分析和侧链定位提供服务的网络服务器。特定服务利用侧链构象对局部主链构象的依赖性，这是通过一种结构字母表来描述的，该字母表描述了有限结构原型库中四个残基长度片段的构象。基于这一概念，SCit使用依赖于每个蛋白质局部主链构象的旋转异构体构象集进行侧链定位，并识别具有不太可能构象的侧链。可通过http://bioserv.rpbs.jussieu.fr/SCit访问SCit网络服务器。
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