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FAN：核苷酸序列的指纹分析。

FAN: fingerprint analysis of nucleotide sequences.

作者信息

Maudling Neil, Attwood Teresa K

机构信息

School of Biological Sciences and Department of Computer Science, University of Manchester, Manchester M13 9PT, UK.

出版信息

Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W620-3. doi: 10.1093/nar/gkh457.

DOI:10.1093/nar/gkh457
PMID:15215463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC441595/
Abstract

FAN is a server for fingerprint analysis of nucleotide sequences. The server performs a search of submitted nucleotide sequences against the PRINTS database. Searches are performed directly against fingerprints using a codon position specific score matrix (PSSM) approach. The advantages of this approach are increased specificity for coding sequence (CDS) over non-CDS, and increased tolerance to base-substituting and frameshifting sequence errors. Furthermore, there is no need for prior translation of the nucleotide sequences. A web-based interface to the software is available at http://bioinf.man.ac.uk/cgi-bin/neil/ntfront.pl.

摘要

FAN是一个用于核苷酸序列指纹分析的服务器。该服务器会将提交的核苷酸序列与PRINTS数据库进行比对搜索。搜索是使用密码子位置特异性得分矩阵（PSSM）方法直接针对指纹进行的。这种方法的优点是对编码序列（CDS）的特异性高于非编码序列，并且对碱基替换和移码序列错误的耐受性增强。此外，无需事先对核苷酸序列进行翻译。可通过网址http://bioinf.man.ac.uk/cgi-bin/neil/ntfront.pl访问该软件的基于网络的界面。

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本文引用的文献

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