Schwebke Jane R, Desmond Renee A, Oh M Kim
Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA.
Sex Transm Dis. 2004 Jul;31(7):433-6. doi: 10.1097/01.olq.0000129948.91055.9f.
Risk factors for bacterial vaginosis (BV) include douching and sexual activity, although the exact cause of BV is unknown.
The goal of this study was to determine the relative significance of douching as a risk factor for BV.
Two hundred fifty adolescent women who regularly douched were enrolled into a randomized douching intervention trial. Behavioral questionnaires and testing for sexually transmitted diseases and BV were performed. Associations between baseline characteristics and behaviors were compared for teens who were BV-positive and BV-negative at baseline.
Positive correlates of BV included multiple partners, recent sexual intercourse, douching after menses, recent douching, and gonorrhea. Of these, douching after menses showed the strongest association (odds ratio, 5.11; 95% confidence interval, 1.99-13.15) in a multivariate analysis.
Douching after menses was strongly correlated with BV; however, difficulty remains in trying to evaluate douching and sexual behavior independently.
细菌性阴道病（BV）的危险因素包括灌洗和性行为，尽管BV的确切病因尚不清楚。
本研究的目的是确定灌洗作为BV危险因素的相对重要性。
250名经常进行灌洗的青春期女性被纳入一项随机灌洗干预试验。进行了行为问卷以及性传播疾病和BV检测。比较了基线时BV呈阳性和阴性的青少年的基线特征与行为之间的关联。
BV的正相关因素包括多个性伴侣、近期性交、月经后灌洗、近期灌洗和淋病。在多变量分析中，其中月经后灌洗显示出最强的关联（比值比，5.11；95%置信区间，1.99 - 13.15）。
月经后灌洗与BV密切相关；然而，要独立评估灌洗和性行为仍存在困难。
