Ott David A., Cooley Denton A., Solis Robert T., Harrison Clanton B.
Division of Surgery of The Texas Heart Institute, St. Luke's Episcopal and Texas Children's Hospitals, Houston, Texas.
Cardiovasc Dis. 1980 Mar;7(1):104-111.
Among a consecutive series of 9,279 sternotomies performed during a period of 2(1/2) years, 61 (0.66%) patients developed significant wound complications. Of these, 58 (95.1%) survived. Sternal infection occurred in 36 patients (0.39%). Predisposing factors included chronic obstructive pulmonary disease, diabetes mellitus, obesity, closed chest massage, prolonged assisted ventilation, and excessive bleeding after operation. Positive end expiratory pressure (PEEP) did not, in itself, predispose to sternal dehiscence. Intermittent positive pressure breathing (IPPB) treatments caused excessive coughing, which may have increased the likelihood of dehiscence. Disposable drapes and expeditious surgery probably contributed to the low incidence of wound infection. Early diagnosis, surgical debridement, rewiring and primary closure with substernal drainage, without continuous antibiotic irrigation, resulted in satisfactory resolution in most patients.
在连续2年半时间内进行的9279例胸骨切开术中,61例(0.66%)患者出现了严重的伤口并发症。其中,58例(95.1%)存活。36例(0.39%)发生了胸骨感染。诱发因素包括慢性阻塞性肺疾病、糖尿病、肥胖、胸外按压、长时间辅助通气以及术后出血过多。呼气末正压(PEEP)本身并不会导致胸骨裂开。间歇性正压通气(IPPB)治疗引起过度咳嗽,这可能增加了裂开的可能性。一次性手术巾和快速手术可能有助于降低伤口感染的发生率。早期诊断、手术清创、重新固定钢丝以及胸骨后引流的一期缝合,不进行持续抗生素冲洗,大多数患者均获得了满意的治疗效果。