Brown Raymond S, Nielsen Morten, Gothelf Kurt V
Department of Molecular Biology, Aarhus University, 8000 Aarhus C, Denmark.
Chem Commun (Camb). 2004 Jul 7(13):1464-5. doi: 10.1039/b403956d. Epub 2004 May 27.
DNA-directed coupling of organic modules by formation of stable aluminium-salen complexes, makes possible the subsequent reductive cleavage of disulfide linkers and release of the two oligonucleotide chains attached to each building-block.
通过形成稳定的铝-萨伦配合物实现有机模块的DNA定向偶联,使得随后二硫键连接子的还原裂解以及连接到每个构建模块上的两条寡核苷酸链的释放成为可能。