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[阿霉素与抗疱疹疫苗联合应用于疱疹性角膜炎患者的抗复发疗效]

[The antirelapse effectiveness of amyxin used in combination with antiherpetic vaccine in patients with herpetic keratitis].

作者信息

Moshetova L K, Chernakova G M, Abaeva M R

出版信息

Vestn Oftalmol. 2004 May-Jun;120(3):22-4.

PMID:15216767
Abstract

The efficiency of the combined use of amixin and anti-herpetic vaccination (AHV) to prevent the relapses of herpetic keratitis (HK) is investigated. One hundred and four patients with HK were followed up. The efficiency was found to be higher in the group of patients who received both amixin and AHV: in 29 (87.9%) patients with surface HK and in 10 (90.9%) patients with deep HK. No effect was registered in 4 (12.1%) persons with surface HK and in 1 (9.1%) person with deep HK. Amixin, when combined with AHV, cuts the number of relapses, therefore, it extends the remission period. The suggested scheme of amixin administration is as follow: 125 mg, once per week, for 10 weeks, 10 pills per one treatment course.

摘要

研究了阿昔洛韦与抗疱疹疫苗(AHV)联合使用预防疱疹性角膜炎(HK)复发的效果。对104例HK患者进行了随访。结果发现,同时接受阿昔洛韦和AHV治疗的患者组效果更佳:29例(87.9%)浅层HK患者和10例(90.9%)深层HK患者有效。4例(12.1%)浅层HK患者和1例(9.1%)深层HK患者未见效果。阿昔洛韦与AHV联合使用时,可减少复发次数,因此可延长缓解期。建议的阿昔洛韦给药方案如下:125毫克,每周一次,共10周,每疗程10片。

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